Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL3280212

C=COC(=O)CC=CC(=O)O.N

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.38
GABRR1 P24046 2/20 0.38
GABRR2 P28476 2/20 0.38
BLM P54132 2/20 0.38
LMNA P02545 2/20 0.38
GABRR3 A8MPY1 1/20 0.38
APEX1 P27695 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
TP53 P04637 1/20 0.32
EGLN1 Q9GZT9 1/20 0.32
EGLN3 Q9H6Z9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL211836 0.98 TSHR (0.39) TSHRGABRR1GABRR2BLMLMNA
SCHEMBL6061868 0.96 TSHR (0.38) TSHRGABRR1GABRR2BLMLMNA
Maleic Acid SCHEMBL4981536 0.96 TSHR (0.38) TSHRGABRR1GABRR2BLMLMNA
Acrylic Acid SCHEMBL6444076 0.94 LMNA (0.40) TSHRGABRR1GABRR2BLMLMNA
Vinyl Chloride SCHEMBL259499 0.92 GABRR1 (0.35) TSHRGABRR1GABRR2BLMLMNA
Vinyl Chloride SCHEMBL6562575 0.92 GABRR1 (0.35) TSHRGABRR1GABRR2BLMLMNA
Acetic Acid SCHEMBL6563939 0.92 GABRR1 (0.35) TSHRGABRR1GABRR2BLMLMNA
Acrylic Acid SCHEMBL6562656 0.89 LMNA (0.36) TSHRGABRR1GABRR2BLMLMNA
Methacrylic Acid SCHEMBL4684697 0.87 GABRR1 (0.32) TSHRGABRR1GABRR2BLMLMNA
Acrylic Acid Methyl Ester SCHEMBL4672549 0.84 HCAR2 (0.41) TSHRGABRR1GABRR2BLMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111356501-A Properties to achieve durable cosmetic Performance 生活实验公司 2020-06-30 CN claimed
US-6685952-B1 CONDITIONERS, SHAMPOOS, HAIR COLOR, SKIN LOTIONS; UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-02-03 US claimed
US-20010022967-A1 Hair styling compositions UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2001-09-20 US claimed
US-5730996-A Intercalates and expoliates formed with organic pesticide compounds and compositions containing the same AMCOL INTERNATIONAL CORPORATION (US) 1998-03-24 US claimed
CN-111356501-A Properties to achieve durable cosmetic Performance 生活实验公司 2020-06-30 CN disclosed
US-20170298410-A1 BREAST MILK ETHANOL SCREENING SYSTEM AND METHOD UPSPRING, LTD. (US) 2017-10-19 US disclosed
US-20130040289-A1 BREAST MILK ETHANOL SCREENING SYSTEM AND METHOD UPSPRING LTD. (US) 2013-02-14 US disclosed
US-20100086616-A1 BREAST MILK ETHANOL SCREENING SYSTEM AND METHOD Upspring Ltd., Corporation (US) 2010-04-08 US disclosed
US-7179451-B2 Hair styling compositions UNILEVER HOME & PERSONAL CARE USA DIVISION OF CONOPCO, INC. (US) 2007-02-20 US disclosed
US-6685952-B1 CONDITIONERS, SHAMPOOS, HAIR COLOR, SKIN LOTIONS; UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-02-03 US disclosed
EP-1198217-A1 PERSONAL CARE COMPOSITIONS AND METHODS-HIGH INTERNAL PHASE WATER-IN-VOLATILE SILICONE OIL SYSTEMS UNILEVER PLC (GB) 2002-04-24 EP disclosed
US-20020004035-A1 Hair styling gels HELENE CURTIS, INC. 2002-01-10 US disclosed
US-5730996-A Intercalates and expoliates formed with organic pesticide compounds and compositions containing the same AMCOL INTERNATIONAL CORPORATION (US) 1998-03-24 US disclosed
US-5721306-A EXFOLIATED PLATELETS FORMED BY CONTACTING LAYERED SILICATE MATERIAL WITH INTERCALANT POLYMER AMCOL INTERNATIONAL CORPORATION (US) 1998-02-24 US disclosed
EP-0808568-A1 Intercalates and exfoliates formed with organic pesticide compounds and compositions containing the same AMCOL INTERNATIONAL CORPORATION (US) 1997-11-26 EP disclosed
EP-0747323-A1 Intercalates; exfoliates; process for manufacturing intercalates and exfoliates and composite materials containing same AMCOL INTERNATIONAL CORPORATION (US) 1996-12-11 EP disclosed
EP-0747451-A2 Intercalates and exfoliates formed with oligomers and polymers and composite materials containing same AMCOL INTERNATIONAL CORPORATION (US) 1996-12-11 EP disclosed
US-5578672-A MIXING PHYLLOSILICATE WITH A POLYMER AND LIQUID CARRIER, EXTRUSION THROUGH DIE; COMPOSITES, AUTOMOBILE PARTS AMCOL INTERNATIONAL CORPORATION (US) 1996-11-26 US disclosed
US-5552469-A SILICATE AMCOL INTERNATIONAL CORPORATION (US) 1996-09-03 US disclosed
EP-0524346-A1 Composition and method for protecting hair against thermal degradation and to aid in hair styling HELENE CURTIS, INC. (US) 1993-01-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100086616-A1 BREAST MILK ETHANOL SCREENING SYSTEM AND METHOD CEL, LCT, GALK1 TSHR 1489/4885GABRR1 2710/4885GABRR2 2651/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.