SCHEMBL6564527

SCHEMBL6564527

COC(=O)OC1CCS(OS(=O)(=O)C(F)(F)F)(c2ccccc2)C1

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.34
MAPT P10636 1/20 0.33
RORC P51449 1/20 0.31
CXCR2 P25025 1/20 0.31
STS P08842 1/20 0.31
CHRM3 P20309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6566234 0.89 BCHE (0.31) BCHESTS
SCHEMBL6564536 0.88 NPSR1 (0.35) BCHEMAPTRORC
SCHEMBL6562645 0.86 DRD3 (0.35) BCHECHRM3
SCHEMBL6562810 0.86
SCHEMBL6564005 0.84 L3MBTL1 (0.33) BCHECHRM3
SCHEMBL2675023 0.84 MAPT (0.32) BCHEMAPTRORC
SCHEMBL6562904 0.82
SCHEMBL6564715 0.81
SCHEMBL6564778 0.80 DRD2 (0.32)
SCHEMBL6564010 0.78 DRD3 (0.33) CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0849634-B1 Radiation sensitive resin composition JSR CORP (JP) 2004-03-31 EP disclosed
US-6322949-B2 SULFONIUM COMPOUND AS PHOTOACID GENERATOR JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 2001-11-27 US disclosed
US-20010014427-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 2001-08-16 US disclosed
US-6187504-B1 PHOTOSENSITIVE BLEND CONTAINING A NAPHTHALENE SULFONIUM SULFONATE DERIVATIVE PHOTOACID GENERATOR, RESIN HAVING ALKALI INSOLUBLE GROUPS CLEAVABLE BY ACID, AN ALKALI SOLUBLE RESIN AND A SOLUBILITY CONTROL AGENT; POSITIVES, RESOLUTION JSR CORPORATION (JP) 2001-02-13 US disclosed
EP-0849634-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-06-24 EP disclosed