SCHEMBL6564536

SCHEMBL6564536

CCOC(=O)OC1CCS(OS(=O)(=O)C(F)(F)F)(c2ccccc2)C1

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.35
POLB P06746 1/20 0.35
KMT2A Q03164 4/20 0.33
MEN1 O00255 3/20 0.33
ALDH1A1 P00352 3/20 0.33
HTT P42858 2/20 0.33
TSHR P16473 1/20 0.33
HPGD P15428 1/20 0.33
BCHE P06276 1/20 0.32
PKM P14618 1/20 0.32
HSD11B1 P28845 1/20 0.32
MAPT P10636 3/20 0.32
CYP2C19 P33261 2/20 0.31
CYP2C9 P11712 1/20 0.31
RORC P51449 2/20 0.31
NR1I2 O75469 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6562645 0.92 DRD3 (0.35) ALDH1A1BCHE
SCHEMBL6564005 0.90 L3MBTL1 (0.33) POLBALDH1A1TSHRHPGDBCHE
SCHEMBL6564527 0.88 BCHE (0.34) BCHEMAPTRORC
SCHEMBL6566234 0.86 BCHE (0.31) BCHE
SCHEMBL2674958 0.85 KDM4E (0.33) NPSR1POLBKMT2AMEN1ALDH1A1
SCHEMBL6564778 0.84 DRD2 (0.32) HSD11B1
SCHEMBL6564815 0.81 DRD2 (0.30)
SCHEMBL6562810 0.81
SCHEMBL6564010 0.80 DRD3 (0.33)
SCHEMBL2675037 0.78 MLNR (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0849634-B1 Radiation sensitive resin composition JSR CORP (JP) 2004-03-31 EP disclosed
US-6322949-B2 SULFONIUM COMPOUND AS PHOTOACID GENERATOR JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 2001-11-27 US disclosed
US-20010014427-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 2001-08-16 US disclosed
US-6187504-B1 PHOTOSENSITIVE BLEND CONTAINING A NAPHTHALENE SULFONIUM SULFONATE DERIVATIVE PHOTOACID GENERATOR, RESIN HAVING ALKALI INSOLUBLE GROUPS CLEAVABLE BY ACID, AN ALKALI SOLUBLE RESIN AND A SOLUBILITY CONTROL AGENT; POSITIVES, RESOLUTION JSR CORPORATION (JP) 2001-02-13 US disclosed
EP-0849634-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-06-24 EP disclosed