Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 14/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6564907 | 0.93 | FFAR1 (0.36) | FFAR1ALOX5FFAR4PTGS2NR1H2 | |
| SCHEMBL6565081 | 0.85 | VDR (0.43) | FFAR1ALOX5FFAR4 | |
| SCHEMBL6564056 | 0.84 | MAOB (0.40) | FFAR1FFAR4 | |
| SCHEMBL6564174 | 0.82 | RORC (0.39) | FFAR1FFAR4NR1H2NR1H3 | |
| SCHEMBL6565086 | 0.82 | FFAR1 (0.41) | FFAR1ALOX5FFAR4PTGS2NR1H2 | |
| SCHEMBL6566235 | 0.75 | VDR (0.43) | FFAR1FFAR4PTGS2 | |
| SCHEMBL6882532 | 0.75 | FFAR1 (0.36) | FFAR1ALOX5FFAR4PTGS2 | |
| SCHEMBL6564557 | 0.75 | FFAR1 (0.40) | FFAR1FFAR4NR1H2NR1H3 | |
| SCHEMBL6566237 | 0.71 | FFAR1 (0.42) | FFAR1ALOX5FFAR4PTGS2 | |
| SCHEMBL7611585 | 0.70 | VDR (0.42) | FFAR1ALOX5FFAR4PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831106-B1 | Selective activity on cell proliferation and differentiation without displaying any hypercalcaemiant nature | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-12-14 | — | — | US | disclosed |
| EP-1235777-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-06-16 | — | — | EP | disclosed |
| EP-1235777-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001038303-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | disclosed |