Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 11/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 11/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563622 | 0.87 | KMT2A (0.43) | PPARGEGLN1KMT2A | |
| SCHEMBL6565295 | 0.86 | PPARG (0.36) | PPARGALDH1A1TP53MAPTEGLN1 | |
| SCHEMBL6574043 | 0.76 | RORC (0.41) | ALDH1A1TP53MAPTHPGDNPSR1 | |
| SCHEMBL6563712 | 0.72 | PLAU (0.47) | PPARGEGLN1 | |
| SCHEMBL6561967 | 0.72 | F2 (0.42) | ALDH1A1TP53MAPTPRMT5KMT2A | |
| SCHEMBL7806877 | 0.67 | PPARG (0.49) | PPARGALDH1A1MAPTHPGDEGLN1 | |
| SCHEMBL6563935 | 0.64 | ACACB (0.48) | PPARGHPGD | |
| SCHEMBL8548179 | 0.64 | L3MBTL1 (0.38) | ALDH1A1TP53MAPTHPGDNPSR1 | |
| SCHEMBL5886056 | 0.62 | MAPK14 (0.38) | PPARGHCRTR1HCRTR2 | |
| SCHEMBL5888740 | 0.62 | GFER (0.40) | PPARGEGLN1HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |