SCHEMBL6565207

SCHEMBL6565207

O=c1oc(CCc2nc3ccc(Cl)cc3c(=O)o2)nc2ccc(Cl)cc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
C1R P00736 4/20 0.52
KDM4E B2RXH2 4/20 0.52
ALDH1A1 P00352 1/20 0.52
ELANE P08246 6/20 0.50
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
APEX1 P27695 1/20 0.44
TUBB4A P04350 1/20 0.43
TUBB P07437 1/20 0.43
TUBA3C P0DPH7 1/20 0.43
TUBA1B P68363 1/20 0.43
TUBA4A P68366 1/20 0.43
TUBB4B P68371 1/20 0.43
TUBB3 Q13509 1/20 0.43
TUBB2A Q13885 1/20 0.43
TUBB8 Q3ZCM7 1/20 0.43
TUBA3E Q6PEY2 1/20 0.43
TUBA1A Q71U36 1/20 0.43
TUBA1C Q9BQE3 1/20 0.43
TUBB6 Q9BUF5 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6567259 0.87 C1R (0.52) C1RKDM4EALDH1A1ELANEMEN1
SCHEMBL6350945 0.82 C1R (0.46) C1RKDM4EALDH1A1ELANEAPEX1
SCHEMBL6353490 0.81 ELANE (0.51) C1RKDM4EALDH1A1ELANEMEN1
SCHEMBL6567186 0.80 ELANE (0.50) C1RKDM4EELANEMEN1KMT2A
SCHEMBL6565653 0.80 ELANE (0.68) C1RKDM4EALDH1A1ELANEMEN1
SCHEMBL6565727 0.80 KDM4E (0.52) C1RKDM4EALDH1A1ELANEMEN1
SCHEMBL6567409 0.80 ELANE (0.50) C1RKDM4EELANEMEN1KMT2A
SCHEMBL29851853 0.80 C1R (0.53) C1RKDM4EALDH1A1ELANEMEN1
SCHEMBL6567394 0.79 ELANE (0.49) C1RKDM4EALDH1A1ELANEMEN1
SCHEMBL1812732 0.78 ELANE (0.70) C1RKDM4EALDH1A1ELANEMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0993965-B1 Thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2004-03-31 EP disclosed
US-6440897-B1 BIS-BENZOXAZINONE COMPOUND AS AN ULTRAVIOLET RAY ABSORBING AGENT NIPPON PAPER INDUSTRIES CO LTD (JP) 2002-08-27 US disclosed
EP-0993965-A2 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-04-19 EP disclosed