SCHEMBL6565727

SCHEMBL6565727

O=c1oc(CCc2nc3ccc(Br)cc3c(=O)o2)nc2ccc(Br)cc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.52
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
ALDH1A1 P00352 3/20 0.52
HPGD P15428 2/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2C19 P33261 1/20 0.52
ELANE P08246 6/20 0.50
TP53 P04637 1/20 0.49
MAPT P10636 3/20 0.46
CASP3 P42574 2/20 0.43
PDE10A Q9Y233 1/20 0.43
RXFP1 Q9HBX9 2/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
POLB P06746 2/20 0.41
GLA P06280 1/20 0.41
NR4A1 P22736 1/20 0.41
PPARG P37231 1/20 0.41
RECQL P46063 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL586985 0.91 KDM4E (0.63) KDM4EMEN1KMT2AALDH1A1HPGD
SCHEMBL6567186 0.80 ELANE (0.50) KDM4EMEN1KMT2AELANEMAPT
SCHEMBL6567409 0.80 ELANE (0.50) KDM4EMEN1KMT2AELANEMAPT
SCHEMBL6565207 0.80 C1R (0.52) KDM4EMEN1KMT2AALDH1A1ELANE
SCHEMBL6565653 0.80 ELANE (0.68) KDM4EMEN1KMT2AALDH1A1ELANE
SCHEMBL6567158 0.79 ELANE (0.49) KDM4EMEN1KMT2AALDH1A1HPGD
SCHEMBL3541523 0.78 ELANE (0.70) KDM4EMEN1KMT2AALDH1A1HPGD
SCHEMBL6563908 0.78 KDM4E (0.48) KDM4EMEN1KMT2AALDH1A1HPGD
SCHEMBL6565945 0.78 ELANE (0.55) KDM4EMEN1KMT2AALDH1A1ELANE
SCHEMBL6565665 0.77 TP53 (0.70) KDM4EMEN1KMT2AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0993965-B1 Thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2004-03-31 EP disclosed
US-6440897-B1 BIS-BENZOXAZINONE COMPOUND AS AN ULTRAVIOLET RAY ABSORBING AGENT NIPPON PAPER INDUSTRIES CO LTD (JP) 2002-08-27 US disclosed
EP-0993965-A2 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-04-19 EP disclosed