SCHEMBL6567409

SCHEMBL6567409

O=c1oc(CCc2nc3ccc(I)cc3c(=O)o2)nc2ccc(I)cc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 8/20 0.50
KDM4E B2RXH2 2/20 0.50
C1R P00736 5/20 0.46
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
PDE10A Q9Y233 1/20 0.43
MAPT P10636 1/20 0.40
PARP1 P09874 1/20 0.39
TUBB4A P04350 1/20 0.38
TUBB P07437 1/20 0.38
TUBA3C P0DPH7 1/20 0.38
TUBA1B P68363 1/20 0.38
TUBA4A P68366 1/20 0.38
TUBB4B P68371 1/20 0.38
TUBB3 Q13509 1/20 0.38
TUBB2A Q13885 1/20 0.38
TUBB8 Q3ZCM7 1/20 0.38
TUBA3E Q6PEY2 1/20 0.38
TUBA1A Q71U36 1/20 0.38
TUBA1C Q9BQE3 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6565727 0.80 KDM4E (0.52) ELANEKDM4EC1RMEN1KMT2A
SCHEMBL6565207 0.80 C1R (0.52) ELANEKDM4EC1RMEN1KMT2A
SCHEMBL6565653 0.80 ELANE (0.68) ELANEKDM4EC1RMEN1KMT2A
SCHEMBL6567186 0.80 ELANE (0.50) ELANEKDM4EC1RMEN1KMT2A
SCHEMBL6565331 0.79 ELANE (0.49) ELANEKDM4EC1RMEN1KMT2A
SCHEMBL3539033 0.78 ELANE (0.70) ELANEKDM4EC1RMEN1KMT2A
SCHEMBL6563908 0.78 KDM4E (0.48) ELANEKDM4EMEN1KMT2APDE10A
SCHEMBL6565945 0.78 ELANE (0.55) ELANEKDM4EMEN1KMT2APDE10A
SCHEMBL6565178 0.77 ELANE (0.56) ELANEKDM4EC1RMEN1KMT2A
SCHEMBL6563917 0.76 KDM4E (0.60) ELANEKDM4EC1RKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0993965-B1 Thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2004-03-31 EP disclosed
US-6440897-B1 BIS-BENZOXAZINONE COMPOUND AS AN ULTRAVIOLET RAY ABSORBING AGENT NIPPON PAPER INDUSTRIES CO LTD (JP) 2002-08-27 US disclosed
EP-0993965-A2 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-04-19 EP disclosed