SCHEMBL6567186

SCHEMBL6567186

O=c1oc(CCc2nc3ccc(O)cc3c(=O)o2)nc2ccc(O)cc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 7/20 0.50
MAPT P10636 3/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
KDM4E B2RXH2 2/20 0.50
RAB9A P51151 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
HSD17B10 Q99714 1/20 0.48
PDE2A O00408 1/20 0.45
PDE10A Q9Y233 1/20 0.43
ESRRB O95718 1/20 0.41
ESR1 P03372 1/20 0.41
ESRRA P11474 1/20 0.41
ESR2 Q92731 1/20 0.41
C1R P00736 1/20 0.39
PKLR P30613 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
PARP1 P09874 1/20 0.39
NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6563908 0.81 KDM4E (0.48) ELANEMAPTMEN1KMT2AKDM4E
SCHEMBL6565727 0.80 KDM4E (0.52) ELANEMAPTMEN1KMT2AKDM4E
SCHEMBL6565653 0.80 ELANE (0.68) ELANEMAPTMEN1KMT2AKDM4E
SCHEMBL6567409 0.80 ELANE (0.50) ELANEMAPTMEN1KMT2AKDM4E
SCHEMBL6565207 0.80 C1R (0.52) ELANEMAPTMEN1KMT2AKDM4E
SCHEMBL6565211 0.79 ELANE (0.49) ELANEMAPTMEN1KMT2AKDM4E
SCHEMBL6565072 0.78 KDM4E (0.49) ELANEMAPTMEN1KMT2AKDM4E
SCHEMBL12352004 0.78 ELANE (0.70) ELANEMAPTMEN1KMT2ARAB9A
SCHEMBL6565945 0.78 ELANE (0.55) ELANEMAPTMEN1KMT2AKDM4E
SCHEMBL2539367 0.77 MAPT (0.77) ELANEMAPTMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0993965-B1 Thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2004-03-31 EP disclosed
US-6440897-B1 BIS-BENZOXAZINONE COMPOUND AS AN ULTRAVIOLET RAY ABSORBING AGENT NIPPON PAPER INDUSTRIES CO LTD (JP) 2002-08-27 US disclosed
EP-0993965-A2 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-04-19 EP disclosed