SCHEMBL6565334

SCHEMBL6565334

CCC(c1nc2ccc(I)cc2c(=O)o1)c1nc2ccc(I)cc2c(=O)o1

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
HTT P42858 1/20 0.47
ELANE P08246 11/20 0.42
C1R P00736 3/20 0.39
TYMS P04818 1/20 0.37
PARP1 P09874 1/20 0.36
EIF4A1 P60842 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6565611 0.84 ELANE (0.62) KDM4EALDH1A1HTTELANEC1R
SCHEMBL6567397 0.82 ALDH1A1 (0.48) KDM4EALDH1A1HTTELANEC1R
SCHEMBL6565217 0.82 MAPT (0.47) KDM4EALDH1A1HTTELANE
SCHEMBL6565648 0.82 ELANE (0.48) KDM4EALDH1A1HTTELANETYMS
SCHEMBL6567161 0.82 TP53 (0.51) KDM4EALDH1A1HTTELANE
SCHEMBL6565065 0.80 KDM4E (0.45) KDM4EALDH1A1HTTELANE
SCHEMBL6567413 0.80 KDM4E (0.54) KDM4EALDH1A1HTTC1R
SCHEMBL6565331 0.80 ELANE (0.49) KDM4EALDH1A1HTTELANEC1R
SCHEMBL6567556 0.79 ELANE (0.44) KDM4EALDH1A1HTTELANE
SCHEMBL6566018 0.79 SMN1; SMN2 (0.48) KDM4EALDH1A1HTTELANETYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0993965-B1 Thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2004-03-31 EP disclosed
US-6440897-B1 BIS-BENZOXAZINONE COMPOUND AS AN ULTRAVIOLET RAY ABSORBING AGENT NIPPON PAPER INDUSTRIES CO LTD (JP) 2002-08-27 US disclosed
EP-0993965-A2 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-04-19 EP disclosed