Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.38 |
| ▸ | B3GNT2 | Q9NY97 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563568 | 0.92 | CNR2 (0.39) | HPGDGAAKMT2APOLBNAMPT | |
| SCHEMBL6561973 | 0.86 | JAK1 (0.38) | SMN1; SMN2HPGDCD274KMT2A | |
| SCHEMBL6563686 | 0.83 | F10 (0.46) | SMN1; SMN2HPGDKDM4EALDH1A1GAA | |
| SCHEMBL6561938 | 0.83 | ABL1 (0.36) | HPGDALDH1A1GAARAB9AKMT2A | |
| SCHEMBL6563605 | 0.83 | GAA (0.37) | HPGDALDH1A1GAAKMT2ANPC1 | |
| SCHEMBL7686729 | 0.79 | PTPN11 (0.43) | SMN1; SMN2HPGDKDM4EALDH1A1KMT2A | |
| SCHEMBL7674981 | 0.79 | ABL1 (0.43) | SMN1; SMN2HPGDKDM4EALDH1A1GAA | |
| SCHEMBL6563229 | 0.78 | PLAU (0.37) | KDM4EALDH1A1RAB9AKMT2ANPC1 | |
| SCHEMBL6565533 | 0.78 | ACACB (0.45) | ALDH1A1GAARAB9AKMT2AF10 | |
| SCHEMBL6563627 | 0.77 | PTPN11 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |