Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7674981 | 0.98 | ABL1 (0.43) | PTPN11ACACBMEN1KMT2AABL1 | |
| SCHEMBL6565384 | 0.93 | GRM5 (0.46) | PTPN11ACACBMEN1KMT2AABL1 | |
| SCHEMBL6561858 | 0.91 | GRM5 (0.47) | PTPN11MEN1KMT2AABL1RIN1 | |
| SCHEMBL6565533 | 0.87 | ACACB (0.45) | PTPN11ACACBMEN1KMT2AABL1 | |
| SCHEMBL6561810 | 0.87 | HSD11B1 (0.40) | PTPN11ACACBABL1RIN1ALDH1A1 | |
| SCHEMBL6565339 | 0.86 | HPGD (0.39) | PTPN11ACACBMEN1KMT2AABL1 | |
| SCHEMBL6563002 | 0.86 | HRH3 (0.42) | PTPN11ALDH1A1NAMPTHPGDLMNA | |
| SCHEMBL6563328 | 0.84 | ACACB (0.36) | PTPN11ACACBMEN1KMT2AABL1 | |
| SCHEMBL6563568 | 0.84 | CNR2 (0.39) | MEN1KMT2AABL1RIN1HTT | |
| SCHEMBL6563511 | 0.84 | PTPN11 (0.40) | PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |