Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565221 | 0.92 | SMN1; SMN2 (0.41) | GAAHPGDKMT2APOLBNAMPT | |
| SCHEMBL6561938 | 0.90 | ABL1 (0.36) | CNR2ABL1RIN1GAAUBE2N | |
| SCHEMBL6563605 | 0.87 | GAA (0.37) | GAAHPGDKMT2AMEN1HTT | |
| SCHEMBL7674981 | 0.86 | ABL1 (0.43) | CNR2ABL1RIN1GAAHPGD | |
| SCHEMBL6565533 | 0.85 | ACACB (0.45) | CNR2ABL1RIN1GAAKMT2A | |
| SCHEMBL7686729 | 0.84 | PTPN11 (0.43) | CNR2ABL1RIN1HPGDKMT2A | |
| SCHEMBL7671074 | 0.82 | F10 (0.43) | GAAHPGDTSHRKMT2AMEN1 | |
| SCHEMBL6561810 | 0.81 | HSD11B1 (0.40) | CNR2ABL1RIN1 | |
| SCHEMBL6565339 | 0.80 | HPGD (0.39) | CNR2ABL1RIN1GAAHPGD | |
| SCHEMBL6563229 | 0.80 | PLAU (0.37) | TSHRKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |