Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 8/20 | 0.40 |
| ▸ | F2 | P00734 | 7/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.39 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.39 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563095 | 0.81 | ALDH1A1 (0.38) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL6562044 | 0.81 | NQO2 (0.37) | PRSS1F2NQO2TMPRSS15 | |
| SCHEMBL6561932 | 0.77 | PRSS1 (0.41) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL6563633 | 0.75 | NQO2 (0.37) | PRSS1F2NQO2TMPRSS15 | |
| SCHEMBL6563331 | 0.72 | F2 (0.43) | F2 | |
| SCHEMBL6563528 | 0.72 | PRSS1 (0.51) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL6563705 | 0.71 | PRSS1 (0.35) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL6563280 | 0.70 | NQO2 (0.35) | PRSS1F2PRSS2PRSS3ST14 | |
| SCHEMBL6563152 | 0.69 | F2 (0.43) | PRSS1F2PRSS2PRSS3NQO2 | |
| SCHEMBL6563646 | 0.69 | KMT2A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |