Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6302579 | 0.59 | RAB9A (0.35) | ALDH1A1GAAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL5784661 | 0.56 | MEN1 (0.65) | ALDH1A1KDM4EMAPTSMN1; SMN2MEN1 | |
| SCHEMBL11245716 | 0.56 | HTT (0.55) | SMN1; SMN2MEN1KMT2AADRA1DADRA1A | |
| SCHEMBL12602894 | 0.55 | GRIN1 (0.50) | ALDH1A1GAAKDM4EMAPTLMNA | |
| SCHEMBL23495184 | 0.55 | TSHR (0.63) | ALDH1A1GAAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL5598939 | 0.55 | — | — | |
| SCHEMBL10154068 | 0.54 | ALDH1A1 (0.65) | ALDH1A1GAAKDM4EMAPTMEN1 | |
| SCHEMBL9851181 | 0.54 | KMT2A (0.58) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL654593 | 0.54 | MEN1 (0.59) | ALDH1A1GAAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL24795954 | 0.54 | ADRA1D (0.49) | KDM4EKMT2AADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268429-B1 | VITRONECTIN RECEPTOR ANTAGONIST BICYCLIC COMPOUNDS, PREPARATION METHOD AND COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2004-08-18 | — | — | EP | disclosed |