Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.41 |
| ▸ | CNR2 | P34972 | 4/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6568663 | 0.81 | FAAH (0.39) | EPHX2CNR2CNR1FAAHMAPT | |
| SCHEMBL4348756 | 0.76 | NPSR1 (0.55) | EPHX2MAPTNPSR1ALDH1A1GAA | |
| SCHEMBL3885380 | 0.72 | ALDH1A1 (0.44) | EPHX2CNR1MAPTNPSR1HSD11B1 | |
| SCHEMBL6568607 | 0.69 | POLB (0.35) | MAPTMEN1ALDH1A1GAAHTT | |
| SCHEMBL4341456 | 0.65 | NPC1 (0.41) | EPHX2CNR2CNR1MEN1GAA | |
| SCHEMBL4348906 | 0.64 | EPHX2 (0.73) | EPHX2MAPTNPSR1MEN1HTT | |
| SCHEMBL4342426 | 0.63 | NPC1 (0.40) | EPHX2MAPTHSD11B1MEN1ALDH1A1 | |
| SCHEMBL6565633 | 0.63 | HTT (0.49) | EPHX2CNR2MAPTNPSR1MEN1 | |
| SCHEMBL8848470 | 0.63 | CNR2 (0.56) | EPHX2CNR2FAAHMAPTNPSR1 | |
| SCHEMBL9005229 | 0.62 | KDM4E (0.60) | EPHX2CNR2FAAHMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1402887-A1 | New compounds for the inhibition of undesired cell proliferation and use thereof | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |
| EP-1402888-A1 | The use of substituted carbocyclic compounds as rotamases inhibitors | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |