Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565448 | 0.81 | EPHX2 (0.41) | FAAHMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL6568620 | 0.78 | CA1 (0.36) | ALDH1A1GAALMNANPSR1POLB | |
| SCHEMBL6567254 | 0.74 | — | — | |
| SCHEMBL4348756 | 0.69 | NPSR1 (0.55) | HTTALDH1A1GAAEPHX2LMNA | |
| SCHEMBL4358407 | 0.63 | EPHX2 (0.65) | MEN1KMT2AHTTEPHX2LMNA | |
| SCHEMBL6565655 | 0.63 | EPHX2 (0.50) | MEN1KMT2AHTTALDH1A1GAA | |
| SCHEMBL6565633 | 0.62 | HTT (0.49) | MEN1KMT2AHTTALDH1A1EPHX2 | |
| SCHEMBL4348906 | 0.58 | EPHX2 (0.73) | MEN1KMT2AHTTEPHX2LMNA | |
| SCHEMBL3885380 | 0.57 | ALDH1A1 (0.44) | HTTALDH1A1GAAEPHX2CNR1 | |
| SCHEMBL4341456 | 0.57 | NPC1 (0.41) | MEN1KMT2AHTTGAAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1402887-A1 | New compounds for the inhibition of undesired cell proliferation and use thereof | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |
| EP-1402888-A1 | The use of substituted carbocyclic compounds as rotamases inhibitors | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |