SCHEMBL6565668

SCHEMBL6565668

Nc1ccccc1-c1ncncn1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
IDO1 P14902 4/20 0.47
HSD17B10 Q99714 3/20 0.44
ACE2 Q9BYF1 1/20 0.43
BCHE P06276 1/20 0.41
ACHE P22303 1/20 0.41
HSP90AA1 P07900 2/20 0.40
SMN1; SMN2 Q16637 5/20 0.39
CYP3A4 P08684 1/20 0.39
ALOX15 P16050 1/20 0.39
CASP1 P29466 1/20 0.39
CASP7 P55210 1/20 0.39
ATAD2 Q6PL18 1/20 0.38
GPR68 Q15743 1/20 0.38
DCUN1D1 Q96GG9 1/20 0.37
KDM4E B2RXH2 5/20 0.36
NPC1 O15118 4/20 0.36
GAA P10253 4/20 0.36
RAB9A P51151 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29889875 1.00 ALDH1A1 (0.52) ALDH1A1L3MBTL1IDO1HSD17B10ACE2
SCHEMBL16731968 0.83 ALDH1A1 (0.37) ALDH1A1L3MBTL1IDO1HSD17B10BCHE
SCHEMBL1317752 0.83 ALDH1A1 (0.37) ALDH1A1L3MBTL1IDO1HSD17B10ACE2
SCHEMBL1232419 0.81 ALDH1A1 (0.57) ALDH1A1L3MBTL1IDO1HSD17B10ACE2
SCHEMBL29521927 0.81 ALDH1A1 (0.52) ALDH1A1L3MBTL1IDO1HSD17B10HSP90AA1
SCHEMBL31158157 0.79 CYP3A4 (0.48) ALDH1A1L3MBTL1IDO1HSD17B10HSP90AA1
SCHEMBL8744274 0.77 ALDH1A1 (0.46) ALDH1A1L3MBTL1IDO1HSD17B10ACE2
SCHEMBL13860777 0.75 ALDH1A1 (0.72) ALDH1A1L3MBTL1IDO1HSD17B10ACE2
SCHEMBL29793563 0.75 ALDH1A1 (0.63) ALDH1A1L3MBTL1IDO1HSD17B10ACE2
SCHEMBL10995283 0.75 ALDH1A1 (0.63) ALDH1A1L3MBTL1IDO1HSD17B10ACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117186481-A Polyphenol hydroxyl COFs aerogel rich in hydrogen bond donor, and preparation method and application thereof 中南大学 2023-12-08 CN claimed
CN-117143305-A NH (NH) 2 -COFs@ZnS photocatalytic material and preparation method and application thereof 中南大学 2023-12-01 CN claimed
CN-116925372-A nanocarbon@COFs hybrid material with thienyl core-shell structure and preparation method and application thereof 中南大学 2023-10-24 CN claimed
CN-114713286-B Ti-MOFs@COFs hybrid material with stable core-shell structure and preparation method and application thereof 中南大学 2023-06-20 CN claimed
CN-114713286-A Ti-MOFs @ COFs hybrid material with stable core-shell structure and preparation method and application thereof 中南大学 2022-07-08 CN claimed
US-20260103446-A1 CFTR REGULATORS AND METHODS OF USE THEREOF UNIV CALIFORNIA (US) 2026-04-16 US disclosed
EP-4724059-A1 USE OF CALCIUM SENSING RECEPTOR ANTAGONISTS FOR TREATING OCULAR DISORDERS The Regents of University of California (US) 2026-04-15 EP disclosed
EP-4019501-B1 CFTR REGULATORS AND METHODS OF USE THEREOF UNIV CALIFORNIA (US) 2026-02-04 EP disclosed
US-12503447-B2 CFTR regulators and methods of use thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-12-23 US disclosed
US-20250367207-A1 OCULAR PHARMACEUTICAL COMPOSITIONS UNIV CALIFORNIA (US) 2025-12-04 US disclosed
US-12391654-B2 CFTR regulators and methods of use thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-08-19 US disclosed
US-20250109113-A1 CFTR REGULATORS AND METHODS OF USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2025-04-03 US disclosed
WO-2017112947-A1 CFTR REGULATORS AND METHODS OF USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-06-29 WO disclosed
WO-2017112951-A1 CFTR REGULATORS AND METHODS OF USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-06-29 WO disclosed
WO-2017112950-A1 CFTR REGULATORS AND METHODS OF USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-06-29 WO disclosed
CN-106159327-A Lithium rechargeable battery 凯思普科技有限责任公司 2016-11-23 CN disclosed
CN-102225918-A 1,2,3-thiadiazole formyl urea compounds as well as preparation method and application thereof LIER CHEMICAL CO LTD 2011-10-26 CN disclosed
CN-102061180-A Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display element CHISSO CORP 2011-05-18 CN disclosed
EP-1377627-A2 CONJUGATED HOMO- AND COPOLYMERS COMPRISING SUBSTITUTED OR UNSUBSTITUTED HETEROARYL GROUP, ITS PREPARATION AND USES Cambridge Display Technology Limited (GB) 2004-01-07 EP disclosed
WO-2002083760-A2 CONJUGATED HOMO-AND COPOLYMERS COMPRISING SUBSTITUTED OR UNSUBSTITUTED HETEROARYL GROUP, ITS PREPARATION AND USES CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2002-10-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250367207-A1 OCULAR PHARMACEUTICAL COMPOSITIONS PLA2G2D, PLA2G2C, PLA2G3 ALDH1A1 2594/4885L3MBTL1 4881/4885IDO1 189/4885
US-12391654-B2 CFTR regulators and methods of use thereof CFTR, SLC26A4, CLCN2 ALDH1A1 2135/4885L3MBTL1 4625/4885IDO1 3422/4885
US-20260103446-A1 CFTR REGULATORS AND METHODS OF USE THEREOF CFTR, CLCN2, SLC26A3 ALDH1A1 1179/4885L3MBTL1 4701/4885IDO1 3046/4885
US-12503447-B2 CFTR regulators and methods of use thereof CFTR, SLC26A4, CLCN2 ALDH1A1 2135/4885L3MBTL1 4625/4885IDO1 3422/4885
US-20250109113-A1 CFTR REGULATORS AND METHODS OF USE THEREOF CFTR, SLC26A4, CLCN2 ALDH1A1 2135/4885L3MBTL1 4625/4885IDO1 3422/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.