SCHEMBL6565780

SCHEMBL6565780

CCOc1ccc(CCCO)cc1C(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 3/20 0.41
S1PR1 P21453 2/20 0.41
CYP4F2 P78329 1/20 0.40
CYP4A11 Q02928 1/20 0.40
AGPAT2 O15120 1/20 0.39
RXRA P19793 1/20 0.39
RXRB P28702 1/20 0.39
RXRG P48443 1/20 0.39
PPARA Q07869 1/20 0.39
PDE4D Q08499 3/20 0.39
PTGDR2 Q9Y5Y4 1/20 0.38
KMT2A Q03164 3/20 0.37
S1PR3 Q99500 1/20 0.37
MEN1 O00255 2/20 0.37
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6567720 0.84 TNKS2 (0.49) CALM1CYP4A11PPARAKMT2AMEN1
SCHEMBL6565864 0.80 TUBB4A (0.47) CALM1CYP4F2CYP4A11PPARAKMT2A
SCHEMBL6565876 0.80 TNKS2 (0.39) CYP4F2CYP4A11PPARAPDE4DKMT2A
SCHEMBL7796630 0.79 RXRA (0.49) S1PR1RXRARXRBRXRGPTGDR2
SCHEMBL7941161 0.79 CYP4F2 (0.48) S1PR1CYP4F2CYP4A11RXRARXRB
SCHEMBL21903454 0.79 S1PR1 (0.46) S1PR1PTGDR2KMT2AMEN1ALDH1A1
SCHEMBL16960215 0.78 SMN1; SMN2 (0.52) CYP4F2CYP4A11AGPAT2
SCHEMBL7796502 0.76 RXRA (0.61) RXRARXRBRXRGPTGDR2ALDH1A1
SCHEMBL2913386 0.76 ALOX15 (0.50) PPARAKMT2AMEN1ALDH1A1KDM4E
SCHEMBL8431708 0.75 RXRA (0.43) RXRARXRBRXRGPTGDR2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1484334-A2 Process for producing phosphite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-08 EP disclosed
US-20040225145-A1 Process for producing phosphite SUMITOMO CHEMICAL COMPANY, LIMITED 2004-11-11 US disclosed
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040225145-A1 Process for producing phosphite PHOSPHO1, PLCG1, PLCG2 CALM1 3581/4885S1PR1 487/4885CYP4F2 387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.