SCHEMBL7796630

SCHEMBL7796630

CCOc1ccc(CCC(=O)O)cc1C(C)(C)C

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RXRA P19793 2/20 0.49
RXRB P28702 2/20 0.49
RXRG P48443 2/20 0.49
FFAR4 Q5NUL3 11/20 0.49
PTGDR2 Q9Y5Y4 1/20 0.49
S1PR1 P21453 2/20 0.48
S1PR3 Q99500 1/20 0.48
S1PR5 Q9H228 1/20 0.48
FFAR1 O14842 8/20 0.48
LMNA P02545 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7792665 0.85 FFAR1 (0.51) RXRARXRBRXRGFFAR4S1PR1
SCHEMBL7796502 0.85 RXRA (0.61) RXRARXRBRXRGPTGDR2LMNA
SCHEMBL2840795 0.83 FFAR4 (0.55) FFAR4FFAR1LMNAL3MBTL1
SCHEMBL9162014 0.83 RXRA (0.47) RXRARXRBRXRGFFAR4PTGDR2
SCHEMBL8984885 0.82 FFAR4 (0.54) RXRAFFAR4PTGDR2S1PR1S1PR3
SCHEMBL7941161 0.82 CYP4F2 (0.48) RXRARXRBRXRGPTGDR2S1PR1
SCHEMBL4009929 0.81 THRB (0.46) RXRARXRBRXRGFFAR1LMNA
SCHEMBL6565780 0.79 CALM1 (0.41) RXRARXRBRXRGPTGDR2S1PR1
SCHEMBL21359040 0.79 FFAR4 (0.51) RXRGFFAR4S1PR1S1PR3S1PR5
SCHEMBL3673329 0.79 FFAR4 (0.61) FFAR4FFAR1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed