SCHEMBL6565891

SCHEMBL6565891

CON1CC(C)N(OC)C1=O

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3236190 0.81 ALDH1A1 (0.41) ALDH1A1
SCHEMBL8643927 0.73 ALDH1A1 (0.31) ALDH1A1
SCHEMBL11612074 0.71 ALDH1A1 (0.35) ALDH1A1
SCHEMBL11812770 0.70 ALDH1A1 (0.34) ALDH1A1
SCHEMBL12108687 0.67
SCHEMBL9401276 0.64 ALDH1A1 (0.33) ALDH1A1
SCHEMBL15362355 0.64 ADRA2C (0.45) ALDH1A1
SCHEMBL19520231 0.62
SCHEMBL18116963 0.60
SCHEMBL11401565 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3963668-A GLASS FIBERS, ALKOXYMETHYL UREAS BASF AKTIENGESELLSCHAFT (DT) 1976-06-15 US claimed
US-20040254064-A1 Method for electrolytic heterocoupling between an aryl(pseudo) halide and an ester containing an ethylenic unsaturation, use of cobalt in order to carry out said coupling and composition therefor RHODIA CHIMIE (FR) 2004-12-16 US disclosed
US-6808655-B1 ELECTROLYSIS ON AN INERT CATHODE LIQUID MIXTURE OF COBALT SALT, ZINC SALT, AND ORGANIC HALIDE; RECOVERING RHODIA CHIMIE (FR) 2004-10-26 US disclosed
EP-1198622-B1 METHOD FOR PREPARING ORGANO-ZINC DERIVATIVES BY ELECTROCHEMICAL PROCESS ASSOCIATED WITH A COBALT SALT CATALYSIS RHODIA CHIMIE SA (FR) 2004-10-06 EP disclosed
US-20040186328-A1 Process of heterocoupling by electrolytic microbattery, use of cobalt for implementing said coupling and composition for doing so RHODIA CHIMIE (FR) 2004-09-23 US disclosed
WO-2004065336-A1 METHOD FOR ELECTROLYTIC MICRO-CELL HETEROCOUPLING, USING COBALT FOR PRODUCING SAID COUPLING AND COMPOSITION THEREFOR RHODIA CHIMIE (FR) 2004-08-05 WO disclosed
EP-1402087-A2 METHOD FOR ELECTROLYTIC HETEROCOUPLING BETWEEN AN ARYL(PSEUDO) HALIDE AND AN ESTER CONTAINING AN ETHYLENIC UNSATURATION, USE OF COBALT IN ORDER TO CARRY OUT SAID COUPLING AND COMPOSITION THEREFOR RHODIA CHIMIE (FR) 2004-03-31 EP disclosed
EP-0906905-B1 Process for the preparation of cyclic ureas BASF AG (DE) 2003-07-30 EP disclosed
WO-2003004729-A2 METHOD FOR ELECTROLYTIC HETEROCOUPLING BETWEEN AN ARYL(PSEUDO) HALIDE AND AN ESTER CONTAINING AN ETHYLENIC UNSATURATION, USE OF COBALT IN ORDER TO CARRY OUT SAID COUPLING AND COMPOSITION THEREFOR RHODIA CHIMIE (FR) 2003-01-16 WO disclosed
EP-1198622-A1 METHOD FOR PREPARING ORGANO-ZINC DERIVATIVES BY ELECTROCHEMICAL PROCESS ASSOCIATED WITH A COBALT SALT CATALYSIS RHODIA CHIMIE (FR) 2002-04-24 EP disclosed
WO-2001002625-A1 METHOD FOR PREPARING ORGANO-ZINC DERIVATIVES BY ELECTROCHEMICAL PROCESS ASSOCIATED WITH A COBALT SALT CATALYSIS RHODIA CHIMIE (FR) 2001-01-11 WO disclosed
US-6103898-A REACTING ACYCLIC UREA DERIVATIVE WITH A DIKETONE, SUBSEQUENT CATALYTIC HYDROGENATION TO FORM CYCLIZED POLAR APROTIC SOLVENT BASF AKTIENGESELLSCHAFT (DE) 2000-08-15 US disclosed
EP-0906905-A1 Process for the preparation of cyclic ureas BASF AKTIENGESELLSCHAFT (DE) 1999-04-07 EP disclosed
US-3963668-A GLASS FIBERS, ALKOXYMETHYL UREAS BASF AKTIENGESELLSCHAFT (DT) 1976-06-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040186328-A1 Process of heterocoupling by electrolytic microbattery, use of cobalt for implementing said coupling and composition for doing so HCN2, HCN1, TET2 ALDH1A1 1250/4885TSHR 3603/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.