Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 2/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12651042 | 0.83 | DDB1 (0.40) | DDB1CRBNMAPTHSD11B1PKM | |
| SCHEMBL10192194 | 0.79 | MAPT (0.53) | DDB1CRBNMAPTL3MBTL1PKM | |
| SCHEMBL10338954 | 0.76 | ALOX5 (0.52) | DDB1CRBNMAPTHSD17B10L3MBTL1 | |
| SCHEMBL7257909 | 0.74 | DDB1 (0.71) | DDB1CRBNMAPTHSD17B10L3MBTL1 | |
| SCHEMBL10814936 | 0.74 | MAPT (0.60) | DDB1CRBNMAPTHSD17B10ALDH1A1 | |
| SCHEMBL8076294 | 0.73 | DDB1 (0.47) | DDB1CRBNMAPTHSD17B10L3MBTL1 | |
| SCHEMBL1788429 | 0.73 | MEN1 (0.58) | DDB1CRBNMAPTL3MBTL1HSD11B1 | |
| SCHEMBL5182235 | 0.73 | DDB1 (0.47) | DDB1CRBNMAPTHSD17B10L3MBTL1 | |
| Hydrochloric Acid SCHEMBL3339995 | 0.72 | HDAC1 (0.46) | CPT2CPT1ACPT1B | |
| SCHEMBL746783 | 0.71 | CRBN (0.66) | DDB1CRBNMAPTKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893453-B1 | Chiral separation of pharmaceutical compounds with charged cyclodextrins using capillary electrophoresis | BECKMAN COULTER INC (US) | 2004-04-07 | — | — | EP | disclosed |
| EP-0893453-A2 | Chiral separation of pharmaceutical compounds with charged cyclodextrins using capillary electrophoresis | Beckman Coulter, Inc. (US) | 1999-01-27 | — | — | EP | disclosed |