Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6564468 | 0.88 | PIK3CD (0.30) | — | |
| Hydrochloric Acid SCHEMBL6564744 | 0.79 | CA12 (0.30) | — | |
| Hydrochloric Acid SCHEMBL6566163 | 0.79 | ADRB2 (0.35) | TSHRALDH1A1ADRB2ADRB1ADRB3 | |
| Hydrochloric Acid SCHEMBL6564457 | 0.77 | ALDH1A1 (0.33) | TSHRALDH1A1ADRB2ADRB1ADRB3 | |
| Hydrochloric Acid SCHEMBL8598314 | 0.75 | ALDH1A1 (0.32) | ALDH1A1ADRB2ADRB1ADRB3 | |
| Hydrochloric Acid SCHEMBL6562668 | 0.73 | DNM1 (0.39) | TSHRALDH1A1ADRB2ADRB1ADRB3 | |
| Hydrochloric Acid SCHEMBL6564480 | 0.73 | DNM1 (0.39) | TSHRALDH1A1ADRB2ADRB1ADRB3 | |
| Hydrochloric Acid SCHEMBL6563811 | 0.72 | ADRB2 (0.36) | TSHRALDH1A1ADRB2ADRB1ADRB3 | |
| Hydrochloric Acid SCHEMBL6566060 | 0.69 | DNM1 (0.39) | TSHR | |
| Hydrochloric Acid SCHEMBL6566107 | 0.69 | DNM1 (0.39) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640627-B1 | Ethylene-alpha-olefin copolymers and molded article thereof | SUMITOMO CHEMICAL CO (JP) | 2004-03-31 | — | — | EP | disclosed |
| EP-0571945-B1 | Catalyst for copolymerizing ethylene with alpha-olefin and process for producing ethylene-alpha-olefin copolymer using the catalyst | SUMITOMO CHEMICAL CO (JP) | 1998-02-04 | — | — | EP | disclosed |
| US-5700895-A | MOLDING MATERIALS; HIGH MELT TENSION, TRANSPARENCY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-23 | — | — | US | disclosed |
| US-5602223-A | RADIATION TRANSPARENT, GLOSS, MELT TENSION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-02-11 | — | — | US | disclosed |
| US-5508364-A | USING A ZIELGER CATALYST CONTAINING A TITANIUM COMPOUND WITH TITANIUM NITROGEN BOND, ORGANOMAGNESIUM AND ORGANOALUMINUM COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-04-16 | — | — | US | disclosed |
| EP-0640627-A1 | Ethylene-alpha-olefin copolymers and molded article thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-03-01 | — | — | EP | disclosed |
| EP-0588567-A1 | An ethylene-alpha-olefin copolymer and a molded article therefrom | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-03-23 | — | — | EP | disclosed |
| EP-0571945-A2 | Catalyst for copolymerizing ethylene with alpha-olefin and process for producing ethylene-alpha-olefin copolymer using the catalyst | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-12-01 | — | — | EP | disclosed |