Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | NAMPT | P43490 | 12/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGAV | P06756 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | CASR | P41180 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6566826 | 0.93 | GAA (0.54) | ALDH1A1NAMPTITGB3ITGAVROCK2 | |
| SCHEMBL6564652 | 0.90 | CASR (0.52) | ALDH1A1NAMPTROCK2ROCK1CASR | |
| SCHEMBL6565755 | 0.90 | L3MBTL1 (0.63) | ALDH1A1NAMPTITGB3ITGAVL3MBTL1 | |
| SCHEMBL6566980 | 0.88 | KMT2A (0.52) | ALDH1A1HTTCASR | |
| SCHEMBL6566505 | 0.88 | LMNA (0.51) | ALDH1A1NAMPTCASR | |
| SCHEMBL6567749 | 0.85 | HTT (0.54) | NAMPTHTTROCK2ROCK1 | |
| SCHEMBL6567996 | 0.84 | GAA (0.53) | ALDH1A1ROCK2CASRL3MBTL1 | |
| SCHEMBL6566680 | 0.83 | CASR (0.56) | ROCK2ROCK1CASR | |
| SCHEMBL6566483 | 0.82 | L3MBTL1 (0.51) | ALDH1A1NAMPTITGB3ITGAVROCK2 | |
| SCHEMBL6564786 | 0.82 | KMT2A (0.61) | ALDH1A1HTTCASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040259912-A1 | Benzine derivatives, process for preparing the same and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-12-23 | — | — | US | disclosed |
| EP-1437344-A1 | BENZENE DERIVATIVES,PROCESS FOR PREPARING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2004-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259912-A1 | Benzine derivatives, process for preparing the same and use thereof | HRH4, HRH2, HRH1 | ALDH1A1 907/4885NAMPT 3240/4885HTT 2150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.