Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NAMPT | P43490 | 8/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGAV | P06756 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6566483 | 0.91 | L3MBTL1 (0.51) | L3MBTL1KMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL6566826 | 0.90 | GAA (0.54) | L3MBTL1KMT2AKDM4EALDH1A1RAB9A | |
| SCHEMBL6566529 | 0.90 | ALDH1A1 (0.56) | L3MBTL1ALDH1A1NAMPTITGB3ITGAV | |
| SCHEMBL6567998 | 0.86 | L3MBTL1 (0.53) | L3MBTL1KMT2ATSHRRAB9ASMN1; SMN2 | |
| SCHEMBL6567020 | 0.84 | KDM4E (0.51) | L3MBTL1KMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL6566680 | 0.82 | CASR (0.56) | KMT2ARAB9ASMN1; SMN2POLB | |
| SCHEMBL6564652 | 0.82 | CASR (0.52) | KMT2AKDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL6567996 | 0.81 | GAA (0.53) | L3MBTL1KMT2AALDH1A1HPGDRAB9A | |
| SCHEMBL6566505 | 0.81 | LMNA (0.51) | KDM4EALDH1A1SMN1; SMN2NAMPT | |
| SCHEMBL6566741 | 0.81 | MEN1 (0.52) | KMT2AALDH1A1RAB9ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040259912-A1 | Benzine derivatives, process for preparing the same and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-12-23 | — | — | US | disclosed |
| EP-1437344-A1 | BENZENE DERIVATIVES,PROCESS FOR PREPARING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2004-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259912-A1 | Benzine derivatives, process for preparing the same and use thereof | HRH4, HRH2, HRH1 | L3MBTL1 2613/4885KMT2A 3137/4885TSHR 1061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.