Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 8/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | HRH2 | P25021 | 2/20 | 0.52 |
| ▸ | HRH1 | P35367 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | GPR183 | P32249 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4381167 | 0.95 | GPR183 (0.53) | PLA2G2ACA12CA1CA2CA9 | |
| SCHEMBL10724043 | 0.83 | SIGMAR1 (0.70) | PLA2G2ACA12CA1CA2CA9 | |
| SCHEMBL10722011 | 0.83 | SIGMAR1 (0.70) | PLA2G2ACA12CA1CA2CA9 | |
| SCHEMBL10723980 | 0.83 | SIGMAR1 (0.70) | PLA2G2ACA12CA1CA2CA9 | |
| SCHEMBL19562089 | 0.82 | CA12 (0.58) | PLA2G2ACA12CA1CA2CA9 | |
| SCHEMBL16980657 | 0.82 | SIGMAR1 (0.72) | PLA2G2AHRH2HRH1DRD2SIGMAR1 | |
| SCHEMBL6488394 | 0.82 | PLA2G2A (0.60) | PLA2G2ACA12CA1CA2CA9 | |
| SCHEMBL6489612 | 0.81 | PLA2G2A (0.54) | PLA2G2ACA12CA1CA2CA9 | |
| SCHEMBL4387836 | 0.80 | HRH3 (0.46) | PLA2G2AGPR183PARP1ALDH1A1 | |
| SCHEMBL1596601 | 0.80 | DRD3 (0.59) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456186-A1 | NOVEL INHIBITOR COMPOUNDS SPECIFIC OF SECRETED NON-PANCREATIC HUMAN A SB 2 /SB PHOSPHOLIPASE OF GROUP II | Yang Ji Chemical Company Ltd. (KR) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003048139-A1 | NOVEL INHIBITOR COMPOUNDS SPECIFIC OF SECRETED NON-PANCREATIC HUMAN A2 PHOSPHOLIPASE OF GROUP II | YANG JI CHEMICAL COMPANY LTD. (KR) | 2003-06-12 | — | — | WO | disclosed |