Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6567074 | 0.86 | ALDH1A1 (0.52) | F10ALDH1A1SMN1; SMN2PRSS1PRSS2 | |
| SCHEMBL6566904 | 0.82 | ALDH1A1 (0.57) | F10ALDH1A1SMN1; SMN2HTTTP53 | |
| SCHEMBL7518683 | 0.80 | F10 (0.77) | F10ALDH1A1SMN1; SMN2PRSS1PRSS2 | |
| SCHEMBL6386373 | 0.80 | F10 (0.65) | F10ALDH1A1SMN1; SMN2PRSS1PRSS2 | |
| SCHEMBL10453043 | 0.80 | ALDH1A1 (0.50) | F10ALDH1A1SMN1; SMN2HTTTP53 | |
| SCHEMBL6387684 | 0.79 | F10 (0.83) | F10ALDH1A1SMN1; SMN2PRSS1PRSS2 | |
| SCHEMBL6565074 | 0.78 | ALDH1A1 (0.64) | F10ALDH1A1SMN1; SMN2PRSS1PRSS2 | |
| SCHEMBL10463338 | 0.78 | ALDH1A1 (0.45) | F10ALDH1A1SMN1; SMN2HTTTP53 | |
| Hydrochloric Acid SCHEMBL6565204 | 0.77 | ALDH1A1 (0.62) | F10ALDH1A1SMN1; SMN2PRSS1PRSS2 | |
| SCHEMBL10461810 | 0.76 | ALDH1A1 (0.54) | F10ALDH1A1SMN1; SMN2HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1443041-A1 | 5-AMIDINO-2-HYDROXYBENZENESULFONAMIDE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME, MEDICINAL USE THEREOF AND INTERMEDIATES IN THE PRODUCTION THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2004-08-04 | — | — | EP | disclosed |