Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BHMT | Q93088 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 2/20 | 0.35 |
| ▸ | GABRD | O14764 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.35 |
| ▸ | GABRE | P78334 | 2/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.35 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.35 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1653844 | 0.89 | SLC22A6 (0.39) | BHMTGRIK1GRIA4GRIK3GRIK5 | |
| Hydrochloric Acid SCHEMBL11804611 | 0.87 | SLC22A6 (0.38) | BHMTGRIK1GRIA4GRIK3GRIK5 | |
| SCHEMBL14486118 | 0.83 | CHRNB2 (0.33) | SLC7A5 | |
| SCHEMBL8679062 | 0.83 | CHRNB2 (0.33) | SLC7A5 | |
| SCHEMBL464909 | 0.83 | GRIK1 (0.31) | SLC7A5GRIK1GRIK2 | |
| SCHEMBL1585736 | 0.81 | SLC7A5 (0.52) | SLC7A5CACNA2D1CACNB3CACNA1CSLC1A3 | |
| SCHEMBL1674752 | 0.81 | GABRR1 (0.33) | BHMTGRIK1GRIA4GRIK3GRIK5 | |
| SCHEMBL7676359 | 0.81 | SLC7A5 (0.52) | SLC7A5CACNA2D1CACNB3CACNA1CSLC1A3 | |
| SCHEMBL14485413 | 0.81 | SLC7A5 (0.52) | SLC7A5CACNA2D1CACNB3CACNA1CSLC1A3 | |
| SCHEMBL1824385 | 0.81 | ALOX15 (0.38) | BHMTGABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1438968-A1 | Topical compositions containing at least one polypeptide hydrolase with an amidasic activity and /or compounds capable of modulating this activity | L'OREAL (FR) | 2004-07-21 | — | — | EP | disclosed |