Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 12/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5969087 | 0.82 | AAK1 (0.52) | PRNPNPSR1RXFP1AAK1MAPT | |
| SCHEMBL5728994 | 0.82 | AAK1 (0.52) | PRNPNPSR1RXFP1AAK1MAPT | |
| SCHEMBL5729717 | 0.82 | AAK1 (0.52) | PRNPNPSR1RXFP1AAK1MAPT | |
| SCHEMBL6568881 | 0.82 | ITGB3 (0.38) | ITGB3ITGA2BSLC6A2MAPTNPC1 | |
| SCHEMBL15564677 | 0.79 | ALDH1A1 (0.43) | ITGB3ITGA2BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6567175 | 0.78 | SLC6A4 (0.39) | ATMSLC6A2SLC6A4MAPTNPC1 | |
| SCHEMBL6567178 | 0.77 | SLC6A4 (0.37) | ATMITGB3ITGA2BSLC6A2SLC6A4 | |
| SCHEMBL5729874 | 0.74 | GSTP1 (0.52) | AAK1MAPTHPGD | |
| SCHEMBL5728927 | 0.74 | GSTP1 (0.52) | AAK1MAPTHPGD | |
| SCHEMBL5969038 | 0.74 | GSTP1 (0.52) | AAK1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1434870-A1 | ENZYMATIC PROCESS FOR THE PREPARATION OF SUBSTITUTED 2-AMINO-3-(2-AMINO-PHENYLSULFANYL)-PROPIONIC ACID | F. HOFFMANN-LA ROCHE AG (CH) | 2004-07-07 | — | — | EP | disclosed |
| WO-2003029477-A1 | ENZYMATIC PROCESS FOR THE PREPARATION OF SUBSTITUTED 2-AMINO-3-(2-AMINO-PHENYLSULFANYL)-PROPIONIC ACID | F. HOFFMANN-LA ROCHE AG (CH) | 2003-04-10 | — | — | WO | disclosed |