Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6567171 | 0.77 | PRNP (0.44) | SLC6A4SLC6A2ATMITGB3ITGA2B | |
| SCHEMBL6567175 | 0.69 | SLC6A4 (0.39) | SLC6A4SLC6A2ATMLMNAALDH1A1 | |
| SCHEMBL16137777 | 0.66 | LMNA (0.45) | ATMLMNAALDH1A1AKR1C2AKR1C1 | |
| SCHEMBL5720982 | 0.66 | SLC2A1 (0.43) | ATMLMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL5720891 | 0.65 | LMNA (0.40) | ATMLMNAALDH1A1HSD17B10AKR1C2 | |
| SCHEMBL4966326 | 0.65 | LMNA (0.48) | LMNAALDH1A1ITGB3ITGA2BMEN1 | |
| SCHEMBL19027086 | 0.64 | KMT2A (0.43) | LMNAALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL28568015 | 0.63 | NOD1 (0.59) | ITGB3ITGA2BMEN1KMT2ANOD1 | |
| SCHEMBL4726420 | 0.63 | CTSL (0.56) | ALDH1A1ITGB3ITGA2BCYP3A4TSHR | |
| SCHEMBL12062829 | 0.63 | CTSL (0.56) | ALDH1A1ITGB3ITGA2BCYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1434870-A1 | ENZYMATIC PROCESS FOR THE PREPARATION OF SUBSTITUTED 2-AMINO-3-(2-AMINO-PHENYLSULFANYL)-PROPIONIC ACID | F. HOFFMANN-LA ROCHE AG (CH) | 2004-07-07 | — | — | EP | disclosed |
| WO-2003029477-A1 | ENZYMATIC PROCESS FOR THE PREPARATION OF SUBSTITUTED 2-AMINO-3-(2-AMINO-PHENYLSULFANYL)-PROPIONIC ACID | F. HOFFMANN-LA ROCHE AG (CH) | 2003-04-10 | — | — | WO | disclosed |