Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14844667 | 0.73 | ALDH1A1 (0.41) | ATMLMNAALDH1A1HSD17B10TSHR | |
| SCHEMBL3639558 | 0.72 | SCN9A (0.48) | SLC6A4LMNAALDH1A1HSD17B10TSHR | |
| SCHEMBL10937504 | 0.70 | METAP2 (0.44) | LMNAALDH1A1HSD17B10TSHRCYP3A4 | |
| SCHEMBL6567178 | 0.69 | SLC6A4 (0.37) | SLC6A4SLC6A2ATMLMNAALDH1A1 | |
| SCHEMBL8549633 | 0.69 | LMNA (0.51) | LMNAALDH1A1HSD17B10TSHRCYP1A2 | |
| SCHEMBL10662822 | 0.68 | ACE (0.41) | LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7373318 | 0.68 | ALDH1A1 (0.44) | ATMLMNAALDH1A1HSD17B10TSHR | |
| SCHEMBL4642323 | 0.67 | ALPI (0.49) | LMNAALDH1A1HSD17B10TSHRCYP3A4 | |
| SCHEMBL2367085 | 0.67 | SMN1; SMN2 (0.39) | ATMLMNAALDH1A1HSD17B10TSHR | |
| SCHEMBL6259632 | 0.66 | ALDH1A1 (0.42) | ATMLMNAALDH1A1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1434870-A1 | ENZYMATIC PROCESS FOR THE PREPARATION OF SUBSTITUTED 2-AMINO-3-(2-AMINO-PHENYLSULFANYL)-PROPIONIC ACID | F. HOFFMANN-LA ROCHE AG (CH) | 2004-07-07 | — | — | EP | disclosed |
| WO-2003029477-A1 | ENZYMATIC PROCESS FOR THE PREPARATION OF SUBSTITUTED 2-AMINO-3-(2-AMINO-PHENYLSULFANYL)-PROPIONIC ACID | F. HOFFMANN-LA ROCHE AG (CH) | 2003-04-10 | — | — | WO | disclosed |