Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28543629 | 0.93 | MEN1 (0.48) | NPC1L3MBTL1RAB9ASMN1; SMN2CTBP2 | |
| SCHEMBL28470738 | 0.83 | MAOB (0.49) | CTBP2MAOBLOXL2CYP2A6MAOA | |
| SCHEMBL354299 | 0.81 | NPC1 (0.50) | NPC1L3MBTL1RAB9ASMN1; SMN2CTBP2 | |
| SCHEMBL163962 | 0.80 | MAOA (0.50) | L3MBTL1TSHRMAPTMAOBMAOA | |
| SCHEMBL1515736 | 0.79 | CTBP2 (0.54) | NPC1L3MBTL1RAB9ASMN1; SMN2CTBP2 | |
| SCHEMBL23837129 | 0.78 | MAOA (0.36) | MAOBMAOAKMT2AMEN1FFAR1 | |
| SCHEMBL11015736 | 0.77 | LMNA (0.55) | TSHRMAOBMAOAALDH1A1LMNA | |
| SCHEMBL8462506 | 0.77 | LOXL2 (0.52) | CTBP2MAOBLOXL2CYP2A6MAOA | |
| SCHEMBL2448732 | 0.76 | L3MBTL1 (0.52) | NPC1L3MBTL1RAB9ACTBP2MAPT | |
| SCHEMBL6546365 | 0.76 | TP53 (0.50) | RAB9ASMN1; SMN2MAOBMAOAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446371-A1 | METHOD FOR THE PRODUCTION OF VINYL-ARENES, -HETEROARENES AND 1,3-DIENES FROM ARYL-, HETEROARYL- OR VINYL-CARBOXYLIC ACID DERIVATIVES | Studiengesellschaft Kohle mbH (DE) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003043958-A1 | METHOD FOR THE PRODUCTION OF VINYL-ARENES, -HETEROARENES AND 1,3-DIENES FROM ARYL-, HETEROARYL- OR VINYL-CARBOXYLIC ACID DERIVATIVES | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2003-05-30 | — | — | WO | disclosed |