SCHEMBL6567325

SCHEMBL6567325

CCC(C)(C)c1cc(CCO)cc(C)c1OC

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RARG P13631 1/20 0.33
RXRA P19793 1/20 0.33
PPARG P37231 1/20 0.33
ALDH1A1 P00352 1/20 0.33
NR3C1 P04150 1/20 0.31
NR3C2 P08235 1/20 0.31
TNKS2 Q9H2K2 1/20 0.30
CYP4F2 P78329 1/20 0.30
CYP4A11 Q02928 1/20 0.30
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
HTR2B P41595 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6567445 0.91 TNKS2 (0.41) RARGRXRAPPARGALDH1A1TNKS2
SCHEMBL6567275 0.87 TNKS2 (0.33) NR3C1NR3C2TNKS2
SCHEMBL6567472 0.86 DHFR (0.38) RARGRXRAPPARGALDH1A1TNKS2
SCHEMBL6567280 0.86 DHFR (0.37) ALDH1A1NR3C1NR3C2TNKS2HTR2A
SCHEMBL6567276 0.85 PTGS2 (0.38)
SCHEMBL6565760 0.84 MAPT (0.36) RARGRXRAPPARGCYP4F2CYP4A11
SCHEMBL7792867 0.83 FFAR4 (0.41) RARGRXRAPPARGALDH1A1KMT2A
SCHEMBL7940316 0.82 ALDH1A1 (0.42) ALDH1A1CYP4F2CYP4A11KMT2A
SCHEMBL4166761 0.80 ALDH1A1 (0.42) ALDH1A1NR3C1NR3C2TNKS2CYP4F2
SCHEMBL3814419 0.80 ESR1 (0.39) ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1484334-A2 Process for producing phosphite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-08 EP disclosed
US-20040225145-A1 Process for producing phosphite SUMITOMO CHEMICAL COMPANY, LIMITED 2004-11-11 US disclosed
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040225145-A1 Process for producing phosphite PHOSPHO1, PLCG1, PLCG2 RARG 3143/4885RXRA 3059/4885PPARG 3687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.