SCHEMBL6565760

SCHEMBL6565760

CCc1cc(CCO)cc(C(C)(C)CC)c1OC

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.36
RARG P13631 1/20 0.35
RXRA P19793 1/20 0.35
PPARG P37231 1/20 0.35
HSPA5 P11021 1/20 0.33
DHFR P00374 2/20 0.32
PTGS2 P35354 1/20 0.32
CYP4F2 P78329 2/20 0.31
CYP4A11 Q02928 2/20 0.31
PPARA Q07869 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6567746 0.92 TNKS2 (0.40) MAPTRARGRXRAPPARGHSPA5
SCHEMBL6565884 0.89 MAPT (0.35) MAPTHSPA5DHFRPTGS2CYP4F2
SCHEMBL6567449 0.88 HSPA5 (0.41) MAPTHSPA5DHFRPTGS2CYP4F2
SCHEMBL6565887 0.85 CNR2 (0.37) MAPTPTGS2
SCHEMBL6567472 0.85 DHFR (0.38) MAPTRARGRXRAPPARGHSPA5
SCHEMBL7796410 0.85 THRA (0.39) RARGRXRAPPARGPPARA
SCHEMBL7942509 0.84 KMT2A (0.39) MAPTRARGRXRAPPARGCYP4F2
SCHEMBL6567325 0.84 RARG (0.33) RARGRXRAPPARGCYP4F2CYP4A11
SCHEMBL6565863 0.82 TNKS2 (0.39) MAPTHSPA5DHFRPTGS2CYP4F2
SCHEMBL7792544 0.81 THRB (0.40) RARGRXRAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1484334-A2 Process for producing phosphite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-08 EP disclosed
US-20040225145-A1 Process for producing phosphite SUMITOMO CHEMICAL COMPANY, LIMITED 2004-11-11 US disclosed
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040225145-A1 Process for producing phosphite PHOSPHO1, PLCG1, PLCG2 MAPT 4868/4885RARG 3143/4885RXRA 3059/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.