Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.30 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29438383 | 0.81 | MAOA (0.45) | MAOAMAOBGAANPSR1TSHR | |
| SCHEMBL667761 | 0.81 | MAOA (0.45) | MAOAMAOBGAANPSR1TSHR | |
| SCHEMBL30098325 | 0.78 | MAOA (0.42) | MAOAMAOBGAANPSR1NPC1 | |
| SCHEMBL6603955 | 0.73 | SMN1; SMN2 (0.37) | GAANPSR1TSHRNPC1LMNA | |
| SCHEMBL4542533 | 0.71 | MAOA (0.46) | MAOAMAOBGAANPSR1TSHR | |
| SCHEMBL971330 | 0.70 | MAOA (0.70) | MAOAMAOBGAANPSR1TSHR | |
| SCHEMBL30360775 | 0.70 | MAOA (0.70) | MAOAMAOBGAANPSR1TSHR | |
| SCHEMBL13189924 | 0.68 | MAOA (0.40) | MAOAMAOBGAANPSR1TSHR | |
| SCHEMBL18790513 | 0.68 | MAOA (0.54) | MAOAMAOBGAANPSR1NPC1 | |
| SCHEMBL311687 | 0.68 | MAOB (0.39) | MAOAMAOBGAANPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1403256-A1 | FUSED IMIDAZOLE DERIVATIVE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-31 | — | — | EP | disclosed |