Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | OXTR | P30559 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL971330 | 0.79 | MAOA (0.70) | MAOAMAOBGAANPSR1NPC1 | |
| SCHEMBL30360775 | 0.79 | MAOA (0.70) | MAOAMAOBGAANPSR1NPC1 | |
| Xanthene SCHEMBL20969988 | 0.71 | MAOA (0.81) | MAOAMAOBGAANPSR1NPC1 | |
| SCHEMBL6567554 | 0.71 | MAOA (0.42) | MAOAMAOBGAANPSR1NPC1 | |
| SCHEMBL4500547 | 0.70 | MAOA (0.64) | MAOAMAOBGAANPSR1NPC1 | |
| SCHEMBL12773597 | 0.70 | MAOA (0.50) | MAOAMAOBGAANPSR1NPC1 | |
| SCHEMBL7295118 | 0.70 | MAOA (0.50) | MAOAMAOBGAANPSR1NPC1 | |
| Dihydrocoumarin SCHEMBL17629427 | 0.70 | MAOB (0.50) | MAOAMAOBGAANPSR1NPC1 | |
| SCHEMBL13950592 | 0.70 | MAOA (0.50) | MAOAMAOBGAANPSR1NPC1 | |
| SCHEMBL5733780 | 0.70 | MAOA (0.50) | MAOAMAOBGAANPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192675-A1 | NEAR AND SHORTWAVE INFRARED POLYMETHINE DYES | UNITED STATES DEPARTMENT OF ENERGY | 2023-06-22 | — | — | US | claimed |
| EP-3606927-A1 | NEAR AND SHORTWAVE INFRARED POLYMETHINE DYES | Massachusetts Institute of Technology (US) | 2020-02-12 | — | — | EP | claimed |
| WO-2018187295-A1 | NEAR AND SHORTWAVE INFRARED POLYMETHINE DYES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-10-11 | — | — | WO | claimed |
| US-9963474-B2 | Mitochondria-targeted dicarbonyl sequestering compounds | MEDICAL RESEARCH COUNCIL (GB) | 2018-05-08 | — | — | US | claimed |
| US-20160289252-A1 | MITOCHONDRIA-TARGETED DICARBONYL SEQUESTERING COMPOUNDS | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2016-10-06 | — | — | US | claimed |
| EP-3071582-A1 | MITOCHONDRIA-TARGETED DICARBONYL SEQUESTERING COMPOUNDS | Medical Research Council (GB) | 2016-09-28 | — | — | EP | claimed |
| WO-2015075200-A1 | MITOCHONDRIA-TARGETED DICARBONYL SEQUESTERING COMPOUNDS | MEDICAL RESEARCH COUNCIL (GB) | 2015-05-28 | — | — | WO | claimed |
| US-20250179130-A1 | METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS | ON TARGET THERAPEUTICS LLC | 2025-06-05 | — | — | US | disclosed |
| US-12060397-B2 | Soluble lipidated ligand agents for treating eye inflammation | TUFTS MEDICAL CENTER (US) | 2024-08-13 | — | — | US | disclosed |
| US-12043619-B2 | Near and shortwave infrared polymethine dyes | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-07-23 | — | — | US | disclosed |
| US-20230192675-A1 | NEAR AND SHORTWAVE INFRARED POLYMETHINE DYES | UNITED STATES DEPARTMENT OF ENERGY | 2023-06-22 | — | — | US | disclosed |
| US-20220135633-A1 | METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS | ON TARGET THERAPEUTICS LLC | 2022-05-05 | — | — | US | disclosed |
| WO-2022037592-A1 | PYRIMIDINE RING COMPOUND | 南京明德新药研发有限公司 | 2022-02-24 | — | — | WO | disclosed |
| EP-2674161-A1 | FMO3 inhibitors for treating pain | Akron Molecules GmbH (AT) | 2013-12-18 | — | — | EP | disclosed |
| CN-103415286-A | Compounds and methods for treating pain | AKRON MOLECULES GMBH | 2013-11-27 | — | — | CN | disclosed |
| WO-2013167743-A1 | USE OF COMPOUNDS FOR THE TREATMENT OF PAIN | AKRON MOLECULES GMBH (AT) | 2013-11-14 | — | — | WO | disclosed |
| US-20130252924-A1 | Compounds and Methods for Treating Pain | AKRON MOLECULES GMBH (AT) | 2013-09-26 | — | — | US | disclosed |
| EP-2637649-A2 | COMPOUNDS AND METHODS FOR TREATING PAIN | Akron Molecules GmbH (AT) | 2013-09-18 | — | — | EP | disclosed |
| WO-2012062925-A2 | COMPOUNDS AND METHODS FOR TREATING PAIN | AKRON MOLECULES GMBH (AT) | 2012-05-18 | — | — | WO | disclosed |
| EP-1174430-A1 | Process for the preparation of heterocycles by using C1-building blocks | Universität Konstanz (DE) | 2002-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220135633-A1 | METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS | LDLR, HDLBP, LIPG | MAOA 4017/4885MAOB 4302/4885GAA 2062/4885 |
| US-12043619-B2 | Near and shortwave infrared polymethine dyes | FHIT, QDPR, PMS2 | MAOA 91/4885MAOB 150/4885GAA 2839/4885 |
| US-20230192675-A1 | NEAR AND SHORTWAVE INFRARED POLYMETHINE DYES | FHIT, QDPR, PMS2 | MAOA 91/4885MAOB 150/4885GAA 2839/4885 |
| US-20130252924-A1 | Compounds and Methods for Treating Pain | TRPV1, ACHE, OPRL1 | MAOA 900/4885MAOB 529/4885GAA 894/4885 |
| US-20160289252-A1 | MITOCHONDRIA-TARGETED DICARBONYL SEQUESTERING COMPOUNDS | NDUFAB1, HADHB, SLC25A21 | MAOA 3387/4885MAOB 1922/4885GAA 624/4885 |
| US-20250179130-A1 | METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS | LDLR, HDLBP, LIPG | MAOA 4017/4885MAOB 4302/4885GAA 2062/4885 |
| US-12060397-B2 | Soluble lipidated ligand agents for treating eye inflammation | LIPG, CD40, LDLR | MAOA 4056/4885MAOB 4400/4885GAA 3161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.