Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | TACR2 | P21452 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6570589 | 0.99 | CNR2 (0.38) | HDAC3HDAC1HDAC2HDAC6ALOX5 | |
| SCHEMBL6570393 | 0.92 | THRA (0.42) | HDAC3HDAC1HDAC2HDAC6ALOX5 | |
| SCHEMBL6569158 | 0.91 | THRA (0.40) | HDAC3HDAC1HDAC2HDAC6ALOX5 | |
| SCHEMBL6568426 | 0.90 | CALM1 (0.38) | HDAC3HDAC1HDAC2HDAC6TRPV1 | |
| SCHEMBL6570523 | 0.87 | CALM1 (0.38) | HDAC3HDAC1HDAC2HDAC6TRPV1 | |
| SCHEMBL6568363 | 0.85 | CALM1 (0.36) | HDAC3HDAC1HDAC2HDAC6KDM4E | |
| SCHEMBL6569451 | 0.85 | PARP1 (0.38) | SLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL6570579 | 0.82 | CALM1 (0.38) | HDAC3HDAC1HDAC2HDAC6TRPV1 | |
| SCHEMBL6569390 | 0.81 | SCN9A (0.33) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6568376 | 0.79 | GRIN2D (0.38) | HDAC3HDAC1HDAC2HDAC6SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1405851-A1 | Method for producing seven-membered diether compounds and intermediates thereof | Takasago International Corporation (JP) | 2004-04-07 | — | — | EP | disclosed |