Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 2/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6568363 | 0.93 | CALM1 (0.36) | CALM1HDAC1HDAC3HDAC2HDAC6 | |
| SCHEMBL6570579 | 0.92 | CALM1 (0.38) | CALM1SKP2TRPV1HDAC1HDAC3 | |
| SCHEMBL6570589 | 0.91 | CNR2 (0.38) | CALM1TRPV1HDAC1HDAC3HDAC2 | |
| SCHEMBL6567583 | 0.90 | HDAC3 (0.39) | TRPV1HDAC1HDAC3HDAC2HDAC6 | |
| SCHEMBL6570523 | 0.86 | CALM1 (0.38) | CALM1SKP2TRPV1HDAC1HDAC3 | |
| SCHEMBL6568376 | 0.86 | GRIN2D (0.38) | CALM1HDAC1HDAC3HDAC2HDAC6 | |
| SCHEMBL6569230 | 0.84 | TAAR1 (0.34) | CALM1TAAR1NPSR1 | |
| SCHEMBL6569099 | 0.83 | TAAR1 (0.36) | CALM1TAAR1CNR2HPGD | |
| SCHEMBL6569158 | 0.83 | THRA (0.40) | CALM1TRPV1HDAC1HDAC3HDAC2 | |
| SCHEMBL6569451 | 0.82 | PARP1 (0.38) | CALM1TAAR1RAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1405851-A1 | Method for producing seven-membered diether compounds and intermediates thereof | Takasago International Corporation (JP) | 2004-04-07 | — | — | EP | disclosed |