Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | TACR2 | P21452 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6570393 | 0.99 | THRA (0.42) | THRATHRBCNR2ALOX5HDAC1 | |
| SCHEMBL6570523 | 0.96 | CALM1 (0.38) | THRATHRBCNR2CALM1HDAC1 | |
| SCHEMBL6570589 | 0.92 | CNR2 (0.38) | CNR2CALM1ALOX5HDAC1HDAC3 | |
| SCHEMBL6567583 | 0.91 | HDAC3 (0.39) | THRATHRBCNR2ALOX5HDAC1 | |
| SCHEMBL6570579 | 0.91 | CALM1 (0.38) | THRATHRBCNR2CALM1HDAC1 | |
| SCHEMBL6569099 | 0.85 | TAAR1 (0.36) | CNR2CALM1KDM4ELMNACYP3A4 | |
| SCHEMBL6567593 | 0.85 | PARP1 (0.39) | SLC6A2SLC6A4SLC6A3KDM4ECYP3A4 | |
| SCHEMBL6568426 | 0.83 | CALM1 (0.38) | CNR2CALM1HDAC1HDAC3HDAC2 | |
| SCHEMBL6569112 | 0.81 | SCN9A (0.34) | CALM1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6567693 | 0.80 | GRIN2D (0.38) | CALM1HDAC1HDAC3HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1405851-A1 | Method for producing seven-membered diether compounds and intermediates thereof | Takasago International Corporation (JP) | 2004-04-07 | — | — | EP | disclosed |