Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6569451 | 0.90 | PARP1 (0.38) | PARP1KMT2AMEN1CYP3A4MAPT | |
| SCHEMBL6570523 | 0.86 | CALM1 (0.38) | RAB9ANPSR1TAAR1 | |
| SCHEMBL6569158 | 0.85 | THRA (0.40) | CYP3A4SLC6A2SLC6A4SLC6A3KDM4E | |
| SCHEMBL6570393 | 0.84 | THRA (0.42) | CYP3A4SLC6A2SLC6A4SLC6A3KDM4E | |
| SCHEMBL6568390 | 0.84 | TAAR1 (0.40) | KMT2AMEN1CYP3A4MAPTCYP2D6 | |
| SCHEMBL6567367 | 0.83 | KDM4E (0.40) | RAB9ASLC6A2KDM4ETSHR | |
| SCHEMBL28614086 | 0.83 | KDM4E (0.40) | RAB9ASLC6A2KDM4ETSHR | |
| SCHEMBL6569099 | 0.82 | TAAR1 (0.36) | KMT2AMEN1CYP3A4TAAR1KDM4E | |
| SCHEMBL6569112 | 0.82 | SCN9A (0.34) | KMT2ACYP2D6ALOX12NPSR1TAAR1 | |
| SCHEMBL6569249 | 0.81 | CYP3A4 (0.55) | PARP1KMT2AMEN1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1405851-A1 | Method for producing seven-membered diether compounds and intermediates thereof | Takasago International Corporation (JP) | 2004-04-07 | — | — | EP | disclosed |