Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6567593 | 0.81 | PARP1 (0.39) | CYP3A4MAPTCYP1A2MEN1KMT2A | |
| SCHEMBL6570523 | 0.77 | CALM1 (0.38) | CNR2HPGDNPSR1 | |
| SCHEMBL28614086 | 0.77 | KDM4E (0.40) | ALDH1A1GAAKDM4EAKR1B1SMN1; SMN2 | |
| SCHEMBL6567367 | 0.77 | KDM4E (0.40) | ALDH1A1GAAKDM4EAKR1B1SMN1; SMN2 | |
| SCHEMBL6569158 | 0.76 | THRA (0.40) | CYP3A4ALDH1A1CNR2KDM4EPTGS1 | |
| SCHEMBL6568390 | 0.75 | TAAR1 (0.40) | CYP3A4MAPTMEN1KMT2AGAA | |
| SCHEMBL6570393 | 0.75 | THRA (0.42) | CYP3A4ALDH1A1CNR2KDM4EPTGS1 | |
| SCHEMBL6569068 | 0.74 | ALOX15 (0.39) | MAPTCYP1A2SMN1; SMN2CYP2D6 | |
| SCHEMBL6569246 | 0.73 | ALDH1A1 (0.37) | MAPTALDH1A1HPGDNPSR1POLB | |
| SCHEMBL6569099 | 0.73 | TAAR1 (0.36) | CYP3A4MEN1KMT2ACNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1405851-A1 | Method for producing seven-membered diether compounds and intermediates thereof | Takasago International Corporation (JP) | 2004-04-07 | — | — | EP | disclosed |