Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | USP5 | P45974 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740216 | 0.85 | TDP1 (0.61) | RAB9AL3MBTL1ALDH1A1NPC1KMT2A | |
| SCHEMBL11631684 | 0.84 | L3MBTL1 (0.62) | RAB9AL3MBTL1ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL27327027 | 0.81 | NPC1 (0.70) | RAB9AL3MBTL1ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL10070199 | 0.80 | USP5 (0.65) | RAB9AL3MBTL1ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL9699992 | 0.80 | TSHR (0.50) | RAB9AALDH1A1NPC1SMN1; SMN2KMT2A | |
| SCHEMBL16174749 | 0.78 | USP5 (0.47) | RAB9AL3MBTL1ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL29011329 | 0.78 | CYP2C9 (0.61) | RAB9AL3MBTL1ALDH1A1NPC1SMN1; SMN2 | |
| Phenyl Propionic Acid SCHEMBL6567856 | 0.78 | KEAP1 (0.59) | RAB9AL3MBTL1ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL28381430 | 0.77 | USP5 (0.44) | RAB9AL3MBTL1ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL21359733 | 0.76 | CYP2C9 (0.44) | RAB9AL3MBTL1ALDH1A1NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401510-A1 | BIODEGRADABLE POLYMER SYSTEMS | Smith & Nephew PLC (GB) | 2004-03-31 | — | — | EP | disclosed |
| WO-2003004071-A1 | BIODEGRADABLE POLYMER SYSTEMS | SMITH & NEPHEW PLC (GB) | 2003-01-16 | — | — | WO | disclosed |