Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | TOP1 | P11387 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11443998 | 0.92 | SLC6A3 (0.60) | KMT2ASMN1; SMN2MAPTSLC6A3ESR1 | |
| SCHEMBL8917839 | 0.90 | SMN1; SMN2 (0.47) | KMT2ASMN1; SMN2MAPTSLC6A3ESR1 | |
| SCHEMBL10500194 | 0.85 | KMT2A (0.50) | KMT2ASMN1; SMN2MAPTSLC6A3ESR1 | |
| SCHEMBL11514420 | 0.84 | NPC1 (0.65) | KMT2ASMN1; SMN2MAPTSLC6A3ESR1 | |
| SCHEMBL6969932 | 0.84 | KMT2A (0.59) | KMT2ASMN1; SMN2MAPTSLC6A3ESR1 | |
| SCHEMBL1697190 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2GAANPSR1LPAR1LPAR5 | |
| SCHEMBL28794462 | 0.82 | ESR1 (0.61) | KMT2ASMN1; SMN2MAPTSLC6A3ESR1 | |
| SCHEMBL9480342 | 0.81 | LMNA (0.46) | KMT2ASMN1; SMN2MAPTSLC6A3ESR1 | |
| SCHEMBL26111795 | 0.81 | NPC1 (0.39) | KMT2ASMN1; SMN2MAPTSLC6A3GAA | |
| SCHEMBL124189 | 0.81 | SMN1; SMN2 (0.49) | SMN1; SMN2GAANPSR1MAPK14NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103030631-A | Compound for preparing pyrimidinedione DPP-IV (dipeptidyl peptidase IV) inhibitors | JIANGSU CHIA TAI TIANQING PHAR | 2013-04-10 | — | — | CN | claimed |
| JP-54085191-A | — | — | None | — | — | JP | disclosed |
| JP-54083694-A | — | — | None | — | — | JP | disclosed |
| JP-53003979-A | — | — | None | — | — | JP | disclosed |
| CN-103030631-B | Compound for preparing pyrimidinedione DPP-IV (dipeptidyl peptidase IV) inhibitors | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD | 2014-12-10 | — | — | CN | disclosed |
| CN-103030631-A | Compound for preparing pyrimidinedione DPP-IV (dipeptidyl peptidase IV) inhibitors | JIANGSU CHIA TAI TIANQING PHAR | 2013-04-10 | — | — | CN | disclosed |
| CN-1176898-C | Fluoro 4-alkene-benzoic acid and its derivative, nematic liquid crystal composition and liquid crystal display using this composition | 大日本油墨化学工业株式会社 | 2004-11-24 | — | — | CN | disclosed |
| EP-0919536-B1 | Fluorine-substituted 4-alkenylbenzoic acid and derivatives thereof, and nematic liquid crystal composition containing cyanophenyl benzoate derivatives and liquid crystal display system using the same | DAINIPPON INK & CHEMICALS (JP) | 2004-04-07 | — | — | EP | disclosed |
| EP-0919536-B1 | Fluorine-substituted 4-alkenylbenzoic acid and derivatives thereof, and nematic liquid crystal composition containing cyanophenyl benzoate derivatives and liquid crystal display system using the same | DAINIPPON INK & CHEMICALS (JP) | 2004-04-07 | — | — | EP | disclosed |
| US-6693223-B1 | STRONG POLAR COMPOUND HAVING LARGE DIELECTRIC ANISOTROPY; EXERTS EXCELLENT THRESHOLD VOLTAGE REDUCING EFFECT; EXCELLENT MISCIBILITY WITH CONVENTIONAL LIQUID CRYSTAL MATERIALS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2004-02-17 | — | — | US | disclosed |
| US-5073294-A | Liquid crystal polymers | HERCULES INCORPORATED (US) | 1991-12-17 | — | — | US | disclosed |
| EP-0445629-A2 | Process of preparing liquid crystal compositions containing multiple oriented mesogens | HERCULES INCORPORATED (US) | 1991-09-11 | — | — | EP | disclosed |
| EP-0395006-A2 | Display composition, coloring pigment, and recording material | SONY CORPORATION (JP) | 1990-10-31 | — | — | EP | disclosed |
| US-4957352-A | Electrochromic display device | SONY CORPORATION (JP) | 1990-09-18 | — | — | US | disclosed |
| EP-0301513-A2 | Electrochromic display | SONY CORPORATION (JP) | 1989-02-01 | — | — | EP | disclosed |
| JP-S5485191-A | LIQUID CRYSTAL COMPOSITION | SHARP CORP | 1979-07-06 | — | — | JP | disclosed |
| JP-S5483694-A | NEMATIC LIQUID CRYSTAL BODY FOR DISPLAY DEVICE | HITACHI LTD | 1979-07-03 | — | — | JP | disclosed |
| US-4082428-A | AROMATIC ESTERS | SUNCRUX INCORPORATED (US) | 1978-04-04 | — | — | US | disclosed |
| US-4082428-A | AROMATIC ESTERS | SUNCRUX INCORPORATED (US) | 1978-04-04 | — | — | US | disclosed |
| JP-S533979-A | LIQUID CRYSTAL COMPOSITION | DAINIPPON TORYO CO LTD | 1978-01-14 | — | — | JP | disclosed |