Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | FABP7 | O15540 | 1/20 | 0.40 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL124189 | 0.86 | SMN1; SMN2 (0.49) | SMN1; SMN2GAAMAPK1ALDH1A1HPGD | |
| SCHEMBL6962495 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2GAAMAPK1ALDH1A1HPGD | |
| SCHEMBL27689216 | 0.84 | ALDH1A1 (0.49) | SMN1; SMN2GAAMAPK1ALDH1A1HPGD | |
| SCHEMBL6567956 | 0.83 | KMT2A (0.58) | SMN1; SMN2GAAMAPK1TSHRTP53 | |
| SCHEMBL11824600 | 0.82 | SMN1; SMN2 (0.54) | SMN1; SMN2GAAMAPK1ALDH1A1HPGD | |
| SCHEMBL28656061 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2GAAMAPK1ALDH1A1HPGD | |
| SCHEMBL5473941 | 0.82 | PTGS2 (0.52) | SMN1; SMN2GAAMAPK1ALDH1A1HPGD | |
| SCHEMBL28899389 | 0.80 | SMN1; SMN2 (0.51) | SMN1; SMN2GAAMAPK1ALDH1A1HPGD | |
| SCHEMBL14775394 | 0.80 | FABP7 (0.43) | SMN1; SMN2ALDH1A1HPGDTSHRNPC1 | |
| SCHEMBL28867820 | 0.79 | HPGD (0.54) | SMN1; SMN2GAAMAPK1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151884-A1 | USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE | PARSONS C LOWELL (US) | 2025-07-17 | — | — | WO | claimed |
| US-20170189443-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF DISEASES AND CONDITIONS EMPLOYING ORAL ADMINISTRATION OF SODIUM PENTOSAN POLYSULFATE AND OTHER PENTOSAN POLYSULFATE SALTS | PLATINUM MONTAUR LIFE SCIENCES, LLC AND AS AGENT (KY) | 2017-07-06 | — | — | US | claimed |
| EP-2895537-B1 | FLAME-RESISTANT POLYCARBONATE FILM | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2017-03-01 | — | — | EP | claimed |
| EP-3110427-A1 | COMPOSITIONS OF PENTOSAN POLYSULFATE SALTS FOR ORAL ADMINISTRATION AND METHODS OF USE | Urigen Pharmaceuticals, Inc. (US) | 2017-01-04 | — | — | EP | claimed |
| US-9228067-B2 | Flame-resistant polycarbonate film | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2016-01-05 | — | — | US | claimed |
| WO-2015127416-A1 | COMPOSITIONS OF PENTOSAN POLYSULFATE SALTS FOR ORAL ADMINISTRATION AND METHODS OF USE | URIGEN PHARMACEUTICALS, INC. (US) | 2015-08-27 | — | — | WO | claimed |
| EP-2895537-A1 | FLAME-RESISTANT POLYCARBONATE FILM | SABIC Global Technologies B.V. (NL) | 2015-07-22 | — | — | EP | claimed |
| US-8771829-B2 | Flame retardant thermoplastic polymer composition, method of manufacture, and articles formed therefrom | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2014-07-08 | — | — | US | claimed |
| CN-102159643-B | Flame retardant thermoplastic polymer compositions, methods of manufacture, and articles formed therefrom | SABIC INNOVATIVE PLASTICS IP | 2014-04-30 | — | — | CN | claimed |
| US-20140079934-A1 | FLAME-RESISTANT POLYCARBONATE FILM | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2014-03-20 | — | — | US | claimed |
| CN-101516968-A | Thermoplastic compositions, methods of making, and articles formed therefrom | SABIC INNOVATIVE PLASTICS IP (NL) | 2009-08-26 | — | — | CN | claimed |
| EP-2066728-A2 | THERMOPLASTIC COMPOSITIONS, METHODS OF MAKING, AND ARTICLES FORMED THEREFROM | Sabic Innovative Plastics IP B.V. (NL) | 2009-06-10 | — | — | EP | claimed |
| WO-2008060714-A9 | THERMOPLASTIC COMPOSITIONS, METHODS OF MAKING, AND ARTICLES FORMED THEREFROM | SABIC INNOVATIVE PLASTICS IP (NL) | 2008-12-24 | — | — | WO | claimed |
| WO-2008127424-A1 | THERMOPLASTIC COMPOSITIONS, METHODS OF MAKING, AND ARTICLES FORMED THEREFROM | SABIC INNOVATIVE PLASTICS IP BV (US) | 2008-10-23 | — | — | WO | claimed |
| WO-2008060714-A2 | THERMOPLASTIC COMPOSITIONS, METHODS OF MAKING, AND ARTICLES FORMED THEREFROM | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-05-22 | — | — | WO | claimed |
| US-20080081855-A1 | THERMOPLASTIC COMPOSITIONS, METHODS OF MAKING, AND ARTICLES FORMED THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2008-04-03 | — | — | US | claimed |
| US-20080081860-A1 | Low temperature ductility, flowability; cyanophenol endcapped polycarbonate, impact modifier and flame retardant; extrusion molding materials | SABIC INNOVATIVE PLASTICS IP BV (US) | 2008-04-03 | — | — | US | claimed |
| US-20080081892-A1 | THERMOPLASTIC COMPOSITIONS, METHODS OF MAKING, AND ARTICLES FORMED THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2008-04-03 | — | — | US | claimed |
| EP-1360221-A1 | MELT POLYCARBONATE CATALYST SYSTEMS | GENERAL ELECTRIC COMPANY (US) | 2003-11-12 | — | — | EP | claimed |
| WO-2002055584-A1 | MELT POLYCARBONATE CATALYST SYSTEMS | GENERAL ELECTRIC COMPANY (US) | 2002-07-18 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170189443-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF DISEASES AND CONDITIONS EMPLOYING ORAL ADMINISTRATION OF SODIUM PENTOSAN POLYSULFATE AND OTHER PENTOSAN POLYSULFATE SALTS | SI, SLC20A1, SLC20A2 | SMN1; SMN2 366/4885GAA 643/4885MAPK1 3137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.