Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | SCD | O00767 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6566630 | 0.91 | PRMT3 (0.46) | L3MBTL1SMN1; SMN2NAMPTRAB9AKMT2A | |
| SCHEMBL6567749 | 0.89 | HTT (0.54) | NAMPTRAB9AKMT2AMEN1 | |
| SCHEMBL6565755 | 0.86 | L3MBTL1 (0.63) | L3MBTL1SMN1; SMN2NAMPTRAB9ATSHR | |
| SCHEMBL6567978 | 0.84 | MEN1 (0.45) | L3MBTL1SMN1; SMN2NAMPTRECQLRAB9A | |
| SCHEMBL6566548 | 0.83 | NPC1 (0.55) | L3MBTL1SMN1; SMN2RAB9ATSHRKMT2A | |
| SCHEMBL6568066 | 0.82 | EPHX1 (0.49) | SMN1; SMN2NAMPTRAB9AKMT2ANPC1 | |
| SCHEMBL6566515 | 0.82 | NAMPT (0.52) | SMN1; SMN2NAMPTRAB9AKMT2ALMNA | |
| SCHEMBL6566629 | 0.82 | NAMPT (0.53) | NAMPTRAB9ACYP2C9KMT2ANPC1 | |
| SCHEMBL6566625 | 0.81 | PPARA (0.52) | SMN1; SMN2NAMPTKMT2AMEN1 | |
| SCHEMBL6566645 | 0.81 | KDM4E (0.53) | SMN1; SMN2CYP1A2CYP3A4RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040259912-A1 | Benzine derivatives, process for preparing the same and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-12-23 | — | — | US | disclosed |
| EP-1437344-A1 | BENZENE DERIVATIVES,PROCESS FOR PREPARING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2004-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259912-A1 | Benzine derivatives, process for preparing the same and use thereof | HRH4, HRH2, HRH1 | L3MBTL1 2613/4885SMN1; SMN2 2126/4885NAMPT 3240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.