Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 3/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6569353 | 0.94 | TSHR (0.47) | LTB4RSIGMAR1TSHRKMT2AALDH1A1 | |
| SCHEMBL6569934 | 0.86 | TSHR (0.59) | TSHRKMT2AALDH1A1HPGDCYP2C9 | |
| SCHEMBL2576418 | 0.84 | LTB4R (0.46) | LTB4RSIGMAR1TSHRL3MBTL1KMT2A | |
| SCHEMBL7385392 | 0.83 | LTB4R (0.66) | LTB4RTSHRKMT2ATRPA1ALDH1A1 | |
| SCHEMBL17027837 | 0.81 | LTB4R (0.68) | LTB4RTSHRKMT2ATRPA1ALDH1A1 | |
| SCHEMBL6344592 | 0.81 | LTB4R (0.68) | LTB4RTSHRKMT2ATRPA1ALDH1A1 | |
| SCHEMBL17027841 | 0.81 | LTB4R (0.68) | LTB4RTSHRKMT2ATRPA1ALDH1A1 | |
| SCHEMBL6971015 | 0.81 | LTB4R (0.68) | LTB4RTSHRKMT2ATRPA1ALDH1A1 | |
| SCHEMBL3928178 | 0.80 | LTB4R (0.52) | LTB4RTSHRKMT2ATRPA1ALDH1A1 | |
| SCHEMBL560219 | 0.80 | TRPA1 (0.51) | SIGMAR1L3MBTL1MAOAKMT2ATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404325-A2 | METHOD FOR TREATING NERVE INJURY CAUSED BY SURGERY | GUILFORD PHARMACEUTICALS INC. (US) | 2004-04-07 | — | — | EP | disclosed |
| WO-2002096420-A2 | METHOD FOR TREATING NERVE INJURY CAUSED BY SURGERY | GUILFORD PHARMACEUTICALS INC. (US) | 2002-12-05 | — | — | WO | disclosed |
| EP-1105112-A2 | COMPOSITIONS AND USES FOR VISION AND MEMORY DISORDERS | GPI NIL Holdings, Inc. (US) | 2001-06-13 | — | — | EP | disclosed |
| EP-1104298-A2 | HETEROCYCLIC THIOESTERS OR KETONES FOR VISION AND MEMORY DISORDERS | GPI NIL Holdings, Inc. (US) | 2001-06-06 | — | — | EP | disclosed |
| WO-2000009108-A2 | COMPOSITIONS AND USES FOR VISION AND MEMORY DISORDERS | GPI NIL HOLDINGS, INC. (US) | 2000-02-24 | — | — | WO | disclosed |
| WO-2000009479-A2 | HETEROCYCLIC THIOESTERS OR KETONES FOR VISION AND MEMORY DISORDERS | GPI NIL HOLDINGS, INC. (US) | 2000-02-24 | — | — | WO | disclosed |