SCHEMBL6568539

SCHEMBL6568539

CCCCCCOC(=O)NOP(=O)(OC)OCCc1sccc1C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.35
EPHX1 P07099 1/20 0.35
NPC1 O15118 6/20 0.34
RAB9A P51151 6/20 0.34
SMN1; SMN2 Q16637 5/20 0.34
ALDH1A1 P00352 5/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
MAPT P10636 1/20 0.33
GAA P10253 1/20 0.33
HPGD P15428 2/20 0.33
KDM4E B2RXH2 1/20 0.33
CASP3 P42574 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
NAAA Q02083 2/20 0.33
LMNA P02545 2/20 0.33
ESR1 P03372 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6571685 0.80 CTSK (0.44) NPC1RAB9ASMN1; SMN2ALDH1A1GAA
SCHEMBL6568392 0.75 EPHX2 (0.46)
SCHEMBL6570239 0.73 P2RY10 (0.44)
SCHEMBL6568523 0.67 CETP (0.48) NPC1RAB9ASMN1; SMN2GAALMNA
SCHEMBL6568697 0.66 EPHX2 (0.48) ALDH1A1HPGDKDM4ELMNA
SCHEMBL6570149 0.66 EPHX2 (0.48) ALDH1A1HPGDKDM4ELMNA
SCHEMBL6569537 0.66 EPHX2 (0.48) ALDH1A1HPGDKDM4ELMNA
SCHEMBL21142475 0.65 ALOX5 (0.42) ALDH1A1CYP1A2CYP2C9CYP2C19GAA
SCHEMBL25765347 0.64 ALOX5 (0.43) ALDH1A1CYP1A2CYP2C9CYP2C19GAA
O-Xylene SCHEMBL27872109 0.61 ALDH1A1 (0.55) L3MBTL1EPHX1NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1156054-B1 DRUGS CONTAINING PHOSPHORIC ACID DERIVATIVES AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO (JP) 2004-04-14 EP claimed
US-6495533-B1 TUMOR NECROSIS FACTOR INHIBITORS; RHEUMATOID ARTHRITIS, ULCERATIVE COLITIS, CROHN'S DISEASE, HEPATITIS, SEPSIS, HEMORRHAGIC SHOCK, MULTIPLE SCLEROSIS, CEREBRAL INFARCTION, DIABETES, INTERSTITIAL PNEUMONIA, PAIN, HIV ONO PHARMACEUTICAL CO., LTD. (JP) 2002-12-17 US claimed
EP-1156054-A1 DRUGS CONTAINING PHOSPHORIC ACID DERIVATIVES AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 2001-11-21 EP claimed