Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10883879 | 0.80 | APEX1 (0.66) | MAPTALDH1A1KDM4EHPGDDHODH | |
| SCHEMBL6567241 | 0.77 | EPHX1 (0.59) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL6565554 | 0.76 | RAB9A (0.46) | MAPTALDH1A1KDM4EHPGDTP53 | |
| SCHEMBL11408752 | 0.75 | MAPT (0.62) | MAPTALDH1A1KDM4EHPGDTP53 | |
| SCHEMBL6566913 | 0.74 | LMNA (0.59) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL6566879 | 0.73 | DHODH (0.43) | MAPTALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL4343702 | 0.73 | DHODH (0.43) | MAPTALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL10770150 | 0.72 | MEN1 (0.50) | MAPTKDM4EHPGDMEN1POLB | |
| SCHEMBL7750062 | 0.71 | TTR (0.44) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL1706750 | 0.71 | DHODH (0.54) | MAPTALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1402887-A1 | New compounds for the inhibition of undesired cell proliferation and use thereof | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |
| EP-1402888-A1 | The use of substituted carbocyclic compounds as rotamases inhibitors | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |