Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | CES1 | P23141 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.53 |
| ▸ | FEN1 | P39748 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487605 | 0.79 | KMT2A (0.67) | KMT2AHPGDMAPTMEN1MAPK1 | |
| SCHEMBL1200149 | 0.79 | KMT2A (0.67) | KMT2AHPGDMAPTMEN1MAPK1 | |
| Dibenzoylmethane SCHEMBL39582 | 0.78 | MEN1 (1.00) | KMT2AHPGDMAPTMEN1MAPK1 | |
| Dibenzoylmethane SCHEMBL1704711 | 0.78 | MEN1 (1.00) | KMT2AHPGDMAPTMEN1MAPK1 | |
| Dibenzoylmethane SCHEMBL10356288 | 0.78 | MEN1 (1.00) | KMT2AHPGDMAPTMEN1MAPK1 | |
| SCHEMBL547080 | 0.77 | MAPT (0.70) | KMT2AHPGDMAPTMEN1MAPK1 | |
| SCHEMBL14417637 | 0.76 | ERCC5 (0.64) | KMT2AHPGDMAPTMEN1MAPK1 | |
| SCHEMBL5931323 | 0.76 | KMT2A (0.61) | KMT2AHPGDMAPTMEN1MAPK1 | |
| Dibenzoylmethane SCHEMBL11587518 | 0.75 | MEN1 (0.94) | KMT2AHPGDMAPTMEN1MAPK1 | |
| Dibenzoylmethane SCHEMBL4205247 | 0.75 | MEN1 (0.94) | KMT2AHPGDMAPTMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040105875-A1 | Composition containing a secondary or tertiary carbonyl amine, method of use thereof, compounds | L'OREAL (FR) | 2004-06-03 | — | — | US | disclosed |
| EP-1405633-A1 | Composition, particularly for cosmetics containing an aromatic aminoketone | L'OREAL (FR) | 2004-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040105875-A1 | Composition containing a secondary or tertiary carbonyl amine, method of use thereof, compounds | CUTA, COL1A1, COL14A1 | KMT2A 1218/4885HPGD 476/4885MAPT 1352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.