Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.67 |
| ▸ | MEN1 | O00255 | 6/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | CES1 | P23141 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 7/20 | 0.59 |
| ▸ | NPC1 | O15118 | 6/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.57 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.57 |
| ▸ | FEN1 | P39748 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7163238 | 0.83 | NR4A2 (0.61) | KMT2AMEN1CYP3A4HPGDMAPK1 | |
| Dibenzoylmethane SCHEMBL10356288 | 0.81 | MEN1 (1.00) | KMT2AMEN1CYP3A4HPGDMAPK1 | |
| Dibenzoylmethane SCHEMBL1704711 | 0.81 | MEN1 (1.00) | KMT2AMEN1CYP3A4HPGDMAPK1 | |
| Dibenzoylmethane SCHEMBL39582 | 0.81 | MEN1 (1.00) | KMT2AMEN1CYP3A4HPGDMAPK1 | |
| SCHEMBL1201297 | 0.81 | KMT2A (0.62) | KMT2AMEN1HPGDKDM4EMAPT | |
| SCHEMBL11004539 | 0.79 | ERCC5 (0.58) | KMT2AMEN1KDM4EMAPTCES1 | |
| SCHEMBL10606188 | 0.79 | KMT2A (0.61) | KMT2AMEN1CYP3A4HPGDMAPK1 | |
| SCHEMBL6568801 | 0.79 | KMT2A (0.61) | KMT2AMEN1CYP3A4HPGDMAPK1 | |
| SCHEMBL5931323 | 0.79 | KMT2A (0.61) | KMT2AMEN1CYP3A4HPGDMAPK1 | |
| SCHEMBL5160670 | 0.79 | PLOD2 (0.60) | KMT2AMEN1CYP3A4HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057666-B | Synthesis method of 4, 5-disubstituted-2-aminothiazole compound | 沈阳药科大学 | 2023-02-07 | — | — | CN | disclosed |
| CN-114057666-A | Synthesis method of 4, 5-disubstituted-2-aminothiazole compound | 沈阳药科大学 | 2022-02-18 | — | — | CN | disclosed |
| US-10322112-B2 | Compound combinations for attenuation of bacterial virulence | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2019-06-18 | — | — | US | disclosed |
| US-20190119201-A1 | Inhibitors of Quorum Sensing Receptor LasR | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2019-04-25 | — | — | US | disclosed |
| US-20170231962-A1 | Compound Combinations for Attenuation of Bacterial Virulence | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-08-17 | — | — | US | disclosed |
| US-20170231962-A1 | Compound Combinations for Attenuation of Bacterial Virulence | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-08-17 | — | — | US | disclosed |
| CN-102321066-B | Method for producing aryl-aminopropanols | SALTIGO GMBH | 2014-07-23 | — | — | CN | disclosed |
| CN-1445224-B | Process for preparing arylaminopropanols | SALTIGO GMBH | 2012-07-11 | — | — | CN | disclosed |
| CN-102321066-A | The method for preparing the arylamino propyl alcohol | SALTIGO GMBH | 2012-01-18 | — | — | CN | disclosed |
| US-7893281-B2 | Process for preparing arylaminopropanols | LANXESS DEUTSCHLAND GMBH (DE) | 2011-02-22 | — | — | US | disclosed |
| US-7169938-B2 | Process for preparing arylaminopropanols | LANXESS DEUTSCHLAND GMBH (DE) | 2007-01-30 | — | — | US | disclosed |
| US-20030225153-A1 | Process for preparing arylaminopropanols | LANXESS DEUTSCHLAND GMBH (DE) | 2003-12-04 | — | — | US | disclosed |
| CN-1445224-A | Process for preparing arylaminopropanols | BAYER AG (DE) | 2003-10-01 | — | — | CN | disclosed |
| EP-1346977-A1 | Method for producing aryl-aminopropanols | Bayer Aktiengesellschaft (DE) | 2003-09-24 | — | — | EP | disclosed |
| EP-0114059-B1 | METHOD OF PREPARING A POLYAMIDE ACID COMPOSITION FOR PREPARING POLYIMIDE | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-06-14 | — | — | EP | disclosed |
| EP-0083690-B1 | POLYAMIDE ACID COMPOSITION FOR PREPARING POLYIMIDE AND PROCESS FOR PREPARING POLYIMIDE FROM THE SAME | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1986-03-12 | — | — | EP | disclosed |
| US-4515915-A | Polyamide acid composition for preparing polyimide | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-05-07 | — | — | US | disclosed |
| EP-0114059-A2 | Method of preparing a polyamide acid composition for preparing polyimide | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1984-07-25 | — | — | EP | disclosed |
| US-4454276-A | POT LIFE EXTENDING AGENT | Kanegafuchi Chkagaku Kogyo Kabushiki Kaisha (JP) | 1984-06-12 | — | — | US | disclosed |
| EP-0083690-A1 | Polyamide acid composition for preparing polyimide and process for preparing polyimide from the same | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1983-07-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170231962-A1 | Compound Combinations for Attenuation of Bacterial Virulence | PNISR, PGLS, QRFPR | KMT2A 3286/4885MEN1 3990/4885CYP3A4 4776/4885 |
| US-20030225153-A1 | Process for preparing arylaminopropanols | AHR, CYP1A1, CYP1A2 | KMT2A 746/4885MEN1 3279/4885CYP3A4 8/4885 |
| US-10322112-B2 | Compound combinations for attenuation of bacterial virulence | PNISR, BLVRB, PGLS | KMT2A 3318/4885MEN1 4469/4885CYP3A4 4682/4885 |
| US-20190119201-A1 | Inhibitors of Quorum Sensing Receptor LasR | FFAR1, CYSLTR1, LPAR1 | KMT2A 3939/4885MEN1 4652/4885CYP3A4 3438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.